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Categories: Borderline Personality Disorder, Neuropathy

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Chronic Illness Diabetes Neuropathy
Published

Researchers uncover potential non-opioid treatment for chronic pain      (via sciencedaily.com)     Original source 

A new approach to treating neuropathic pain is making a key step forward. Neuropathic pain is among the most difficult types of pain to alleviate and current treatments are often ineffective. Researchers have identified a potential non-opioid treatment.

Healthy Aging Neuropathy Psychology Research Schizophrenia
Published

Firing nerve fibers in the brain are supplied with energy on demand      (via sciencedaily.com)     Original source 

To rapidly transmit electrical signals in the brain, the long nerve fibers are insulated by specialized cells called oligodendrocytes. These cells also respond to the electrical signals of active nerve fibers and provide them with energy on demand, as researchers have discovered. If this process, regulated by potassium, is disabled in mice, the nerve fibers are severely damaged as the animals age -- resembling the defects of neurodegenerative diseases.

Chronic Illness Neuropathy Today's Healthcare
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Good and bad news for people with low back pain      (via sciencedaily.com)     Original source 

Low back pain is a major cause of disability around the globe, with more than 570 million people affected. New research shows that many people with persistent low back pain (more than 12 weeks) continue to have moderate-to-high levels of pain and disability.

Neuropathy Today's Healthcare
Published

Clarifying the cause of Guillain-Barré Syndrome      (via sciencedaily.com)     Original source 

Guillain-?Barr Syndrome is a rare condition in which a person's immune system attacks the peripheral nerves. People affected suffer from muscle weakness and paralysis. A research team led by ETH Zurich has now clarified the mechanism of this autoimmune disease.

Children's Health Healthy Aging Neuropathy Psychology Research
Published

RSV shown to infect nerve cells, cause inflammation and damage      (via sciencedaily.com)     Original source 

RSV, a common infection in children and the elderly thought to only infect the respiratory tract, can also infect nerve cells and cause nerve damage, according to a new study. The findings could have major implications about whether RSV could be connected to neurological or developmental disorders.

Chronic Illness Fitness Neuropathy Today's Healthcare
Published

Different pain types in multiple sclerosis can cause difficulty staying active      (via sciencedaily.com)     Original source 

Chronic pain can present in multiple forms for multiple sclerosis patients. Some forms make it harder to stay active than others.

Neuropathy Psychology Research
Published

Lost brain function restored in mice after stroke      (via sciencedaily.com)     Original source 

Researchers have succeeded in restoring lost brain function in mouse models of stroke using small molecules that in the future could potentially be developed into a stroke recovery therapy.

Neuropathy Today's Healthcare
Published

Common headaches tied to neck inflammation      (via sciencedaily.com)     Original source 

Researchers have identified objective evidence of how the neck muscles are involved in primary headaches, according to a new study.

Neuropathy Nutrition Obesity Psychology Research
Published

Fat cells help repair damaged nerves      (via sciencedaily.com)     Original source 

Damage to the body's peripheral nerves can cause pain and movement disorders. Researchers have recently investigated how damaged nerves can regenerate better. They found that fat tissue strongly supports the Schwann cells needed for repair during the healing process.

Chronic Illness Neuropathy Psychology Research
Published

Repairing nerve cells after injury and in chronic disease      (via sciencedaily.com)     Original source 

Researchers discovered a mechanism for repairing damaged nerves during peripheral neuropathy in mice, wherein the protein Mitf orchestrates nerve repair after both trauma-induced and chronic nerve damage conditions, like Charcot Marie Tooth disease. Their findings may inspire novel therapeutics that bolster repair function and heal peripheral neuropathy -- even in hereditary and developmental cases.

Neuropathy
Published

Getting to the root of visceral gut pain      (via sciencedaily.com)     Original source 

Researchers have uncovered a reason that may explain why visceral pain is so common in conditions like irritable bowel syndrome. This understanding could inspire new and better ways to alleviate that pain.

Dietary Supplements and Minerals Neuropathy Women's Health - General
Published

New compound outperforms pain drug by indirectly targeting calcium channels      (via sciencedaily.com)     Original source 

A compound -- one of 27 million screened in a library of potential new drugs -- reversed four types of chronic pain in animal studies, according to new research. The small molecule, which binds to an inner region of a calcium channel to indirectly regulate it, outperformed gabapentin without troublesome side effects, providing a promising candidate for treating pain.

Chronic Illness Neuropathy
Published

Disturbances in sensory neurons may alter transient pain into chronic pain      (via sciencedaily.com)     Original source 

Researchers have identified that a transient inflammatory pain causes mitochondrial and redox changes in sensory neurons that persist beyond pain resolution. These changes appear to predispose to a failure in resolution of pain caused by a subsequent inflammation. Additionally, targeting the cellular redox balance prevents and treats chronic inflammatory pain in rodents.

Birth Defects Neuropathy Psychology Research
Published

Lab unlocks keys to alcohol withdrawal headache      (via sciencedaily.com)     Original source 

Researchers have discovered mechanisms by which specific cells are activated in alcohol withdrawal-induced headache. The research may benefit further studies of various substance use disorder mechanisms including withdrawal. It may be possible to develop a small-molecule drug therapy to inhibit interactions, resulting in fewer pain signals during alcohol withdrawal.

Chronic Illness Neuropathy Psychology Research Today's Healthcare
Published

New study provides evidence for more effective brain-based treatment of chronic back pain      (via sciencedaily.com)     Original source 

A new study may provide key answers to how to help people experiencing chronic back pain. The study examined the critical connection between the brain and pain for treating chronic pain. Specifically, they looked at the importance of pain attributions, which are people's beliefs about the underlying causes of their pain, to reduce chronic back pain severity.

Neuropathy Psychology Research
Published

Researchers 'bioprint' living brain cell networks in the lab      (via sciencedaily.com)     Original source 

Researchers have successfully used 'bioinks' containing living nerve cells (neurons) to print 3D nerve networks that can grow in the laboratory and transmit and respond to nerve signals.

Neuropathy
Published

Scrambler therapy may offer lasting relief for chronic pain, review paper suggests      (via sciencedaily.com)     Original source 

Pain experts suggest that scrambler therapy, a noninvasive pain treatment, can yield significant relief for approximately 80% -- 90% of patients with chronic pain, and it may be more effective than another noninvasive therapy: transcutaneous electrical nerve stimulation (TENS).

Neuropathy
Published

Gene therapy treats chronic pain by dialing down sodium      (via sciencedaily.com)     Original source 

Scientists identified the region where a protein regulates sodium ion channels, inserting the channel's genetic material into a virus to alleviate pain in cell and animal studies.

Neuropathy
Published

Researchers use the antidepressant tianeptine to manage chronic pain      (via sciencedaily.com)     Original source 

Neuropathic pain is a debilitating condition estimated to affect as much as 10% of the global population. It results from a damaged or malfunctioning nervous system, stemming from diseases like diabetes, alcoholism, strokes, Parkinson's and other causes like spinal nerve compression, radiation and chemotherapy treatments. Management of neuropathic pain has been particularly challenging as currently prescribed drugs, such as anticonvulsants and antidepressants can have severe adverse effects, are not well-tolerated, take a longer time to work only help a subset of patients.

Borderline Personality Disorder Depression Mental Health Research
Published

Neural signature for borderline personality disorder identified      (via sciencedaily.com)     Original source 

A new study of a brain region called the rostro-medial prefrontal could potentially advance diagnosis and therapies for Borderline Personality Disorder (BPD).