Showing 20 articles starting at article 1
Categories: Neuropathy, Schizophrenia
Published Scientists take next big step in understanding genetics of schizophrenia
(via sciencedaily.com) Original source Scientists are figuring out which of the 5,000 variants associated with schizophrenia have an actual causal effect in the development of the condition that affects millions of people worldwide.
Published Schizophrenia genetic risk factor impairs mitochondrial function
(via sciencedaily.com) Original source Researcher discovers possible link of mitochondrial function to the development of schizophrenia.
Published New neuroimaging approach could improve diagnosis of schizophrenia
(via sciencedaily.com) Original source New research has identified age-related changes in brain patterns associated with the risk for developing schizophrenia. The discovery could help clinicians identify the risk for developing mental illness earlier and improve treatment options.
Published Schizophrenia is associated with somatic mutations occurring in utero
(via sciencedaily.com) Original source As a psychiatric disorder with onset in adulthood, schizophrenia is thought to be triggered by some combination of environmental factors and genetics, although the exact cause is still not fully understood. Researchers have now found a correlation between schizophrenia and somatic copy-number variants, a type of mutation that occurs early in development but after genetic material is inherited. This study is one of the first to rigorously describe the relationship between somatic -- not inherited -- genetic mutations and schizophrenia risk.
Published Body's immune response may offer alternative approach to neuropathic pain therapies
(via sciencedaily.com) Original source In the midst of a global opioid epidemic, a team of scientists is exploring natural killer (NK) cells as an alternative treatment for neuropathic pain. Researchers gather existing evidence for the impact of NK cells in pain, pointing to their ability to prune the damaged nerve cells that may cause it. They urge the scientific community to explore biological mechanisms underlying NK cell activity to move towards a realistic pain therapy that is both effective and safe.
Published Pregnancy hormone repairs myelin damage in MS mouse model
(via sciencedaily.com) Original source A new study has identified a treatment that could repair myelin in the cortex, undoing some of the damage caused by MS.
Published How does dopamine regulate both learning and motivation?
(via sciencedaily.com) Original source A new study brings together two schools of thought on the function of the neurotransmitter dopamine: one saying that dopamine provides a learning signal, the other saying that dopamine drives motivation.
Published Further link identified between autoimmunity and schizophrenia
(via sciencedaily.com) Original source Links have been reported between schizophrenia and proteins produced by the immune system that can act against one's own body, known as autoantibodies. Researchers have now identified autoantibodies that target a 'synaptic adhesion protein' in a subset of patients with schizophrenia. When injected into mice, the autoantibodies caused many schizophrenia-related changes.
Published Vitamin D alters developing neurons in the brain's dopamine circuit
(via sciencedaily.com) Original source Neuroscientists have shown how vitamin D deficiency affects developing neurons in the brain's dopamine circuit, which may lead to the dopamine dysfunction seen in adults with schizophrenia.
Published New chemical compound demonstrates potential in nerve regeneration
(via sciencedaily.com) Original source Recent research has identified a new compound that can stimulate nerve regeneration after injury, as well as protect cardiac tissue from the sort of damage seen in heart attack.
Published A special omega-3 fatty acid lipid will change how we look at the developing and aging brain
(via sciencedaily.com) Original source Scientists have found a lipid transporter crucial to regulating the cells that make myelin, the nerve-protecting sheath.
Published Neuropathic pain: The underlying mechanism and a potential therapeutic target are revealed in mice
(via sciencedaily.com) Original source Neuropathic pain -- abnormal hypersensitivity to stimuli -- is associated with impaired quality of life and is often poorly managed. Estimates suggest that 3 percent to 17 percent of adults suffer from neuropathic pain, including a quarter of people with diabetes and a third of people with HIV. Researchers report that a mechanism involving the enzyme Tiam1 in dorsal horn excitatory neurons of the spinal cord both initiates and maintains neuropathic pain. Moreover, they show that targeting spinal Tiam1 with anti-sense oligonucleotides injected into the cerebrospinal fluid effectively alleviated neuropathic pain hypersensitivity.
Published How alcohol consumption contributes to chronic pain
(via sciencedaily.com) Original source A team showed how both alcohol intake and alcohol withdrawal can lead to increased pain and hypersensitivity.
Published Genetic therapy corrects progressive muscle disorder in mice
(via sciencedaily.com) Original source Investigators recently used a targeted drug to restore muscle strength and correct myotonia in mice with myotonic dystrophy.
Published Students engineer socks for on-the-go neuropathy treatment
(via sciencedaily.com) Original source A wearable electrical-stimulation and vibration-therapy system designed by engineering students might be just what the doctor ordered for people experiencing foot pain and balance loss due to diabetic neuropathy.
Published Bariatric surgery may reverse diabetes complications for people with obesity
(via sciencedaily.com) Original source For more than 100 million Americans who are obese, bariatric surgery may reverse complications related to diabetes, including regenerating damaged nerves, a new study shows. Researchers say the findings suggest that bariatric surgery likely enables the regeneration of the peripheral nerves and, therefore, may be an effective treatment for millions of individuals with obesity who are at risk of developing diabetes and peripheral neuropathy,
Published Fibromyalgia: Pain out of control
(via sciencedaily.com) Original source Feeling like we have a degree of control makes us tolerate pain better. In the case of fibromyalgia, however, this simply doesn't work. A study provides clues as to why.
Published Spinal cord stimulation doesn't help with back pain, says new review
(via sciencedaily.com) Original source People with chronic back pain may turn to spinal cord stimulation to ease their pain, but a Cochrane Review found no sustained benefits to the surgery that outweigh the costs and risks.
Published The drug fasudil is found to reverse key symptoms of schizophrenia in mice
(via sciencedaily.com) Original source Researchers used the drug fasudil to restore neurons and improve methamphetamine-induced cognitive dysfunction in a mouse model of schizophrenia.
Published Antidepressants used for chronic pain on the rise, but are they effective?
(via sciencedaily.com) Original source New research has found some antidepressants may be effective in treating certain chronic pain conditions, but others lack convincing evidence on their effectiveness.