Showing 20 articles starting at article 1
Published Birth-control pills affect the body's ability to regulate stress, study suggests (via sciencedaily.com) Original source
A new study suggests that birth-control pills negatively impact women's stress response.
Published Body's immune response may offer alternative approach to neuropathic pain therapies (via sciencedaily.com) Original source
In the midst of a global opioid epidemic, a team of scientists is exploring natural killer (NK) cells as an alternative treatment for neuropathic pain. Researchers gather existing evidence for the impact of NK cells in pain, pointing to their ability to prune the damaged nerve cells that may cause it. They urge the scientific community to explore biological mechanisms underlying NK cell activity to move towards a realistic pain therapy that is both effective and safe.
Published Pregnancy hormone repairs myelin damage in MS mouse model (via sciencedaily.com) Original source
A new study has identified a treatment that could repair myelin in the cortex, undoing some of the damage caused by MS.
Published New study links contraceptive pills and depression (via sciencedaily.com) Original source
Women who used combined contraceptive pills were at greater risk of developing depression than women who did not, according to a new study. Contraceptive pills increased women's risk by 73 per cent during the first two years of use.
Published New chemical compound demonstrates potential in nerve regeneration (via sciencedaily.com) Original source
Recent research has identified a new compound that can stimulate nerve regeneration after injury, as well as protect cardiac tissue from the sort of damage seen in heart attack.
Published Neuropathic pain: The underlying mechanism and a potential therapeutic target are revealed in mice (via sciencedaily.com) Original source
Neuropathic pain -- abnormal hypersensitivity to stimuli -- is associated with impaired quality of life and is often poorly managed. Estimates suggest that 3 percent to 17 percent of adults suffer from neuropathic pain, including a quarter of people with diabetes and a third of people with HIV. Researchers report that a mechanism involving the enzyme Tiam1 in dorsal horn excitatory neurons of the spinal cord both initiates and maintains neuropathic pain. Moreover, they show that targeting spinal Tiam1 with anti-sense oligonucleotides injected into the cerebrospinal fluid effectively alleviated neuropathic pain hypersensitivity.
Published How alcohol consumption contributes to chronic pain (via sciencedaily.com) Original source
A team showed how both alcohol intake and alcohol withdrawal can lead to increased pain and hypersensitivity.
Published New genetic target for male contraception identified (via sciencedaily.com) Original source
Discovery of a gene in multiple mammalian species could pave the way for a highly effective, reversible and non-hormonal male contraceptive for humans and animals. Researchers identified expression of the gene, Arrdc5, in the testicular tissue of mice, pigs, cattle and humans. When they knocked out the gene in mice, it created infertility only in the males, impacting their sperm count, movement and shape.
Published Genetic therapy corrects progressive muscle disorder in mice (via sciencedaily.com) Original source
Investigators recently used a targeted drug to restore muscle strength and correct myotonia in mice with myotonic dystrophy.
Published Students engineer socks for on-the-go neuropathy treatment (via sciencedaily.com) Original source
A wearable electrical-stimulation and vibration-therapy system designed by engineering students might be just what the doctor ordered for people experiencing foot pain and balance loss due to diabetic neuropathy.
Published Bariatric surgery may reverse diabetes complications for people with obesity (via sciencedaily.com) Original source
For more than 100 million Americans who are obese, bariatric surgery may reverse complications related to diabetes, including regenerating damaged nerves, a new study shows. Researchers say the findings suggest that bariatric surgery likely enables the regeneration of the peripheral nerves and, therefore, may be an effective treatment for millions of individuals with obesity who are at risk of developing diabetes and peripheral neuropathy,
Published Fibromyalgia: Pain out of control (via sciencedaily.com) Original source
Feeling like we have a degree of control makes us tolerate pain better. In the case of fibromyalgia, however, this simply doesn't work. A study provides clues as to why.
Published Study finds similar association of progestogen-only and combined hormonal contraceptives with breast cancer risk (via sciencedaily.com) Original source
There is a relative increase of 20% to 30% in breast cancer risk associated with both combined and progesterone-only contraceptives, whatever the mode of delivery, though with five years of use, the 15-year absolute excess incidence is at most 265 cases per 100,000 users, according to a new study.
Published Spinal cord stimulation doesn't help with back pain, says new review (via sciencedaily.com) Original source
People with chronic back pain may turn to spinal cord stimulation to ease their pain, but a Cochrane Review found no sustained benefits to the surgery that outweigh the costs and risks.
Published High infant mortality rates and global human population rise (via sciencedaily.com) Original source
New research showing high infant mortality rates are contributing to an incessant rise of the global human population supports arguments for greater access to contraception and family planning in low- and middle-income nations.
Published On-demand male contraceptive shows promise in preclinical study (via sciencedaily.com) Original source
An experimental contraceptive drug temporarily stops sperm in their tracks and prevents pregnancies in preclinical models. The study demonstrates that an on-demand male contraceptive is possible.
Published Antidepressants used for chronic pain on the rise, but are they effective? (via sciencedaily.com) Original source
New research has found some antidepressants may be effective in treating certain chronic pain conditions, but others lack convincing evidence on their effectiveness.
Published Supplementation with amino acid serine eases neuropathy in diabetic mice (via sciencedaily.com) Original source
The study adds to growing evidence that some often-underappreciated, 'non-essential' amino acids play important roles in the nervous system. The findings may provide a new way to identify people at high risk for peripheral neuropathy, as well as a potential treatment option.
Published Neuroscientists identify a small molecule that restores visual function after optic nerve injury (via sciencedaily.com)
Traumatic injury to the brain, spinal cord and optic nerve in the central nervous system (CNS) are the leading cause of disability and the second leading cause of death worldwide. CNS injuries often result in a catastrophic loss of sensory, motor and visual functions, which is the most challenging problem faced by clinicians and research scientists. Neuroscientists have recently identified and demonstrated a small molecule that can effectively stimulate nerve regeneration and restore visual functions after optic nerve injury, offering great hope for patients with optic nerve injury, such as glaucoma-related vision loss.
Published Treating gut pain via a Nobel prize-winning receptor (via sciencedaily.com)
Targeting a receptor responsible for our sense of touch and temperature, which researchers have now found to be present in our colon, could provide a new avenue for treating chronic pain associated with gastrointestinal disorders such as irritable bowel syndrome. A team examining the colon identified the presence of Piezo2, the subject of the 2021 Nobel Prize in Physiology or Medicine, now known to be responsible for sensing light touch on our skin.