Showing 20 articles starting at article 1
Published Body's immune response may offer alternative approach to neuropathic pain therapies (via sciencedaily.com) Original source
In the midst of a global opioid epidemic, a team of scientists is exploring natural killer (NK) cells as an alternative treatment for neuropathic pain. Researchers gather existing evidence for the impact of NK cells in pain, pointing to their ability to prune the damaged nerve cells that may cause it. They urge the scientific community to explore biological mechanisms underlying NK cell activity to move towards a realistic pain therapy that is both effective and safe.
Published Research challenges current thinking on the genetic causes of very early menopause (via sciencedaily.com) Original source
The genetic causes of very early menopause will have to be reconsidered after researchers found that nearly all women who carried variations thought to cause the condition in fact had their menopause at an older age.
Published Pregnancy hormone repairs myelin damage in MS mouse model (via sciencedaily.com) Original source
A new study has identified a treatment that could repair myelin in the cortex, undoing some of the damage caused by MS.
Published New study links contraceptive pills and depression (via sciencedaily.com) Original source
Women who used combined contraceptive pills were at greater risk of developing depression than women who did not, according to a new study. Contraceptive pills increased women's risk by 73 per cent during the first two years of use.
Published New chemical compound demonstrates potential in nerve regeneration (via sciencedaily.com) Original source
Recent research has identified a new compound that can stimulate nerve regeneration after injury, as well as protect cardiac tissue from the sort of damage seen in heart attack.
Published Neuropathic pain: The underlying mechanism and a potential therapeutic target are revealed in mice (via sciencedaily.com) Original source
Neuropathic pain -- abnormal hypersensitivity to stimuli -- is associated with impaired quality of life and is often poorly managed. Estimates suggest that 3 percent to 17 percent of adults suffer from neuropathic pain, including a quarter of people with diabetes and a third of people with HIV. Researchers report that a mechanism involving the enzyme Tiam1 in dorsal horn excitatory neurons of the spinal cord both initiates and maintains neuropathic pain. Moreover, they show that targeting spinal Tiam1 with anti-sense oligonucleotides injected into the cerebrospinal fluid effectively alleviated neuropathic pain hypersensitivity.
Published How alcohol consumption contributes to chronic pain (via sciencedaily.com) Original source
A team showed how both alcohol intake and alcohol withdrawal can lead to increased pain and hypersensitivity.
Published Osteoporosis treatments may benefit from discovery of key driver of low bone density (via sciencedaily.com) Original source
Scientists have pinpointed a key driver of low bone density, a discovery that may lead to improved treatments with fewer side effects for women with osteoporosis. The findings reveal that loss of an epigenetic modulator, KDM5C, preserves bone mass in mice. KDM5C works by altering epigenetic 'marks,' which are akin to 'on' and 'off' switches that ensure the instructions written in DNA are used at the right time and in the right place.
Published Genetic therapy corrects progressive muscle disorder in mice (via sciencedaily.com) Original source
Investigators recently used a targeted drug to restore muscle strength and correct myotonia in mice with myotonic dystrophy.
Published Students engineer socks for on-the-go neuropathy treatment (via sciencedaily.com) Original source
A wearable electrical-stimulation and vibration-therapy system designed by engineering students might be just what the doctor ordered for people experiencing foot pain and balance loss due to diabetic neuropathy.
Published Bariatric surgery may reverse diabetes complications for people with obesity (via sciencedaily.com) Original source
For more than 100 million Americans who are obese, bariatric surgery may reverse complications related to diabetes, including regenerating damaged nerves, a new study shows. Researchers say the findings suggest that bariatric surgery likely enables the regeneration of the peripheral nerves and, therefore, may be an effective treatment for millions of individuals with obesity who are at risk of developing diabetes and peripheral neuropathy,
Published Fibromyalgia: Pain out of control (via sciencedaily.com) Original source
Feeling like we have a degree of control makes us tolerate pain better. In the case of fibromyalgia, however, this simply doesn't work. A study provides clues as to why.
Published Early menopause, later start to hormone therapy may increase risk of Alzheimer's disease (via sciencedaily.com) Original source
Women are more likely than men to develop Alzheimer's disease (AD), with women making up two-thirds of the population living with AD. A new study sheds light on the relationship between the risk of Alzheimer's disease and age of menopause and use of hormone therapy (HT).
Published Getting a good night's sleep could boost your response to vaccination (via sciencedaily.com) Original source
We all know how important sleep is for mental health, but a meta-analysis found that getting good shut-eye also helps our immune systems respond to vaccination. The authors found that people who slept less than six hours per night produced significantly fewer antibodies than people who slept seven hours or more, and the deficit was equivalent to two months of antibody waning.
Published Spinal cord stimulation doesn't help with back pain, says new review (via sciencedaily.com) Original source
People with chronic back pain may turn to spinal cord stimulation to ease their pain, but a Cochrane Review found no sustained benefits to the surgery that outweigh the costs and risks.
Published Migraines during menstruation: Low estrogen levels paired with higher CGRP levels may jump start migraine (via sciencedaily.com) Original source
As estrogen levels fluctuate, a new study has found for female participants with migraine, their levels of the protein calcitonin gene-related peptide (CGRP) that plays a key role in starting the migraine process also fluctuate.
Published Air pollution speeds bone loss from osteoporosis (via sciencedaily.com) Original source
Elevated levels of air pollutants are associated with bone damage among postmenopausal women, according to new research. The effects were most evident on the lumbar spine, with nitrous oxides twice as damaging to the area than seen with normal aging.
Published Antidepressants used for chronic pain on the rise, but are they effective? (via sciencedaily.com) Original source
New research has found some antidepressants may be effective in treating certain chronic pain conditions, but others lack convincing evidence on their effectiveness.
Published Does lifetime exposure to estrogen affect risk of stroke? (via sciencedaily.com)
People with a higher cumulative estrogen exposure throughout their life may have a lower risk of stroke, according to a new study. The lower risk was found for both ischemic stroke and intracerebral hemorrhage.
Published Supplementation with amino acid serine eases neuropathy in diabetic mice (via sciencedaily.com) Original source
The study adds to growing evidence that some often-underappreciated, 'non-essential' amino acids play important roles in the nervous system. The findings may provide a new way to identify people at high risk for peripheral neuropathy, as well as a potential treatment option.