Showing 20 articles starting at article 1
Published How pre- and postnatal B-12 vitamins improve breast milk vitamin B-12 levels, which supports infant brain development (via sciencedaily.com) Original source
According to a new study B-12 vitamins increase the presence of the micronutrient in mothers' breast milk, which is especially helpful in countries where it can be difficult to eat what is needed for the body to produce B-12 naturally.
Published Lost brain function restored in mice after stroke (via sciencedaily.com) Original source
Researchers have succeeded in restoring lost brain function in mouse models of stroke using small molecules that in the future could potentially be developed into a stroke recovery therapy.
Published Common headaches tied to neck inflammation (via sciencedaily.com) Original source
Researchers have identified objective evidence of how the neck muscles are involved in primary headaches, according to a new study.
Published Novel study finds aspirin-free regimen benefits patients with LVAD (via sciencedaily.com) Original source
The ARIES-HM3 Randomized Clinical Trial assessed the safety and efficacy of excluding aspirin from the antithrombotic regimen in patients with advanced heart failure who have undergone implantation of a fully magnetically levitated left ventricular assist device (LVAD). The clinical trial found that excluding aspirin from the antithrombotic regimen in patients with a levitated left ventricular assist device was safe.
Published Fat cells help repair damaged nerves (via sciencedaily.com) Original source
Damage to the body's peripheral nerves can cause pain and movement disorders. Researchers have recently investigated how damaged nerves can regenerate better. They found that fat tissue strongly supports the Schwann cells needed for repair during the healing process.
Published Repairing nerve cells after injury and in chronic disease (via sciencedaily.com) Original source
Researchers discovered a mechanism for repairing damaged nerves during peripheral neuropathy in mice, wherein the protein Mitf orchestrates nerve repair after both trauma-induced and chronic nerve damage conditions, like Charcot Marie Tooth disease. Their findings may inspire novel therapeutics that bolster repair function and heal peripheral neuropathy -- even in hereditary and developmental cases.
Published Getting to the root of visceral gut pain (via sciencedaily.com) Original source
Researchers have uncovered a reason that may explain why visceral pain is so common in conditions like irritable bowel syndrome. This understanding could inspire new and better ways to alleviate that pain.
Published Study reveals surprising link between malnutrition and rising antibiotic resistance (via sciencedaily.com) Original source
Researchers have uncovered startling connections between micronutrient deficiencies and the composition of gut microbiomes in early life that could help explain why resistance to antibiotics has been rising across the globe. The team investigated how deficiencies in crucial micronutrients such as vitamin A, B12, folate, iron, and zinc affected the community of bacteria, viruses, fungi and other microbes that live in the digestive system. They discovered that these deficiencies led to significant shifts in the gut microbiome of mice -- most notably an alarming expansion of bacteria and fungi known to be opportunistic pathogens. Importantly, mice with micronutrient deficiencies also exhibited a higher enrichment of genes that have been linked to antibiotic resistance.
Published Vitamin B12: A key player in cellular reprogramming and tissue regeneration (via sciencedaily.com) Original source
Researchers reveal that vitamin B12 significantly boosts the efficiency of cellular reprogramming, thus holding promise for regenerative medicine. Vitamin B12 supplementation shows potential in speeding up tissue repair in a model of ulcerative colitis -- an observation that points to potential new treatments for inflammatory diseases.
Published New compound outperforms pain drug by indirectly targeting calcium channels (via sciencedaily.com) Original source
A compound -- one of 27 million screened in a library of potential new drugs -- reversed four types of chronic pain in animal studies, according to new research. The small molecule, which binds to an inner region of a calcium channel to indirectly regulate it, outperformed gabapentin without troublesome side effects, providing a promising candidate for treating pain.
Published Clinical trial data suggests prenatal vitamin D reduces a child's risk of asthma (via sciencedaily.com) Original source
A review of 15 years' worth of data found that vitamin D supplementation during pregnancy was linked to reduced rates of asthma and wheezing in children compared to standard prenatal multivitamin.
Published Reducing vitamin B5 slows breast cancer growth in mice (via sciencedaily.com) Original source
Researchers have discovered that breast cancer cells expressing a cancer-driving gene heavily rely on vitamin B5 to grow and survive.
Published Disturbances in sensory neurons may alter transient pain into chronic pain (via sciencedaily.com) Original source
Researchers have identified that a transient inflammatory pain causes mitochondrial and redox changes in sensory neurons that persist beyond pain resolution. These changes appear to predispose to a failure in resolution of pain caused by a subsequent inflammation. Additionally, targeting the cellular redox balance prevents and treats chronic inflammatory pain in rodents.
Published Lab unlocks keys to alcohol withdrawal headache (via sciencedaily.com) Original source
Researchers have discovered mechanisms by which specific cells are activated in alcohol withdrawal-induced headache. The research may benefit further studies of various substance use disorder mechanisms including withdrawal. It may be possible to develop a small-molecule drug therapy to inhibit interactions, resulting in fewer pain signals during alcohol withdrawal.
Published New study provides evidence for more effective brain-based treatment of chronic back pain (via sciencedaily.com) Original source
A new study may provide key answers to how to help people experiencing chronic back pain. The study examined the critical connection between the brain and pain for treating chronic pain. Specifically, they looked at the importance of pain attributions, which are people's beliefs about the underlying causes of their pain, to reduce chronic back pain severity.
Published Researchers 'bioprint' living brain cell networks in the lab (via sciencedaily.com) Original source
Researchers have successfully used 'bioinks' containing living nerve cells (neurons) to print 3D nerve networks that can grow in the laboratory and transmit and respond to nerve signals.
Published First-in-class targeted microRNA therapy slows cancer tumor growth (via sciencedaily.com) Original source
A new cancer therapy attacks tumors by tricking cancer cells into absorbing a snippet of RNA that naturally blocks cell division.
Published Antioxidants stimulate blood flow in tumors (via sciencedaily.com) Original source
Vitamin C and other antioxidants stimulate the formation of new blood vessels in lung cancer tumors, a new study shows. The discovery corroborates the idea that dietary supplements containing antioxidants can accelerate tumor growth and metastasis.
Published Scrambler therapy may offer lasting relief for chronic pain, review paper suggests (via sciencedaily.com) Original source
Pain experts suggest that scrambler therapy, a noninvasive pain treatment, can yield significant relief for approximately 80% -- 90% of patients with chronic pain, and it may be more effective than another noninvasive therapy: transcutaneous electrical nerve stimulation (TENS).
Published Gene therapy treats chronic pain by dialing down sodium (via sciencedaily.com) Original source
Scientists identified the region where a protein regulates sodium ion channels, inserting the channel's genetic material into a virus to alleviate pain in cell and animal studies.