Showing 20 articles starting at article 1
Published Lost brain function restored in mice after stroke (via sciencedaily.com) Original source
Researchers have succeeded in restoring lost brain function in mouse models of stroke using small molecules that in the future could potentially be developed into a stroke recovery therapy.
Published Twin research indicates that a vegan diet improves cardiovascular health (via sciencedaily.com) Original source
A recent trial of identical twins comparing vegan and omnivore diets found that a vegan diet improves overall cardiovascular health.
Published Common headaches tied to neck inflammation (via sciencedaily.com) Original source
Researchers have identified objective evidence of how the neck muscles are involved in primary headaches, according to a new study.
Published Fat cells help repair damaged nerves (via sciencedaily.com) Original source
Damage to the body's peripheral nerves can cause pain and movement disorders. Researchers have recently investigated how damaged nerves can regenerate better. They found that fat tissue strongly supports the Schwann cells needed for repair during the healing process.
Published Repairing nerve cells after injury and in chronic disease (via sciencedaily.com) Original source
Researchers discovered a mechanism for repairing damaged nerves during peripheral neuropathy in mice, wherein the protein Mitf orchestrates nerve repair after both trauma-induced and chronic nerve damage conditions, like Charcot Marie Tooth disease. Their findings may inspire novel therapeutics that bolster repair function and heal peripheral neuropathy -- even in hereditary and developmental cases.
Published Getting to the root of visceral gut pain (via sciencedaily.com) Original source
Researchers have uncovered a reason that may explain why visceral pain is so common in conditions like irritable bowel syndrome. This understanding could inspire new and better ways to alleviate that pain.
Published New compound outperforms pain drug by indirectly targeting calcium channels (via sciencedaily.com) Original source
A compound -- one of 27 million screened in a library of potential new drugs -- reversed four types of chronic pain in animal studies, according to new research. The small molecule, which binds to an inner region of a calcium channel to indirectly regulate it, outperformed gabapentin without troublesome side effects, providing a promising candidate for treating pain.
Published Disturbances in sensory neurons may alter transient pain into chronic pain (via sciencedaily.com) Original source
Researchers have identified that a transient inflammatory pain causes mitochondrial and redox changes in sensory neurons that persist beyond pain resolution. These changes appear to predispose to a failure in resolution of pain caused by a subsequent inflammation. Additionally, targeting the cellular redox balance prevents and treats chronic inflammatory pain in rodents.
Published Lab unlocks keys to alcohol withdrawal headache (via sciencedaily.com) Original source
Researchers have discovered mechanisms by which specific cells are activated in alcohol withdrawal-induced headache. The research may benefit further studies of various substance use disorder mechanisms including withdrawal. It may be possible to develop a small-molecule drug therapy to inhibit interactions, resulting in fewer pain signals during alcohol withdrawal.
Published Study suggests even more reasons to eat your fiber (via sciencedaily.com) Original source
Health professionals have long praised the benefits of insoluble fiber for bowel regularity and overall health. New research suggests even more reasons we should be prioritizing fiber in our regular diets. Researchers found that each plant source of insoluble fiber contains unique bioactives -- compounds that have been linked to lower incidence of cardiovascular disease, cancer and Type 2 diabetes -- offering potential health benefits beyond those of the fiber itself.
Published The microbiome of fruit and vegetables positively influences diversity in the gut (via sciencedaily.com) Original source
In a meta-study, a research team has provided evidence that the consumption of fruit and vegetables contributes positively to bacterial diversity in the human gut.
Published Being a vegetarian may be partly in your genes (via sciencedaily.com) Original source
A person's genetic makeup plays a role in determining whether they can stick to a strict vegetarian diet, a new study has found. The findings open the door to further studies that could have important implications regarding dietary recommendations and the production of meat substitutes.
Published New study provides evidence for more effective brain-based treatment of chronic back pain (via sciencedaily.com) Original source
A new study may provide key answers to how to help people experiencing chronic back pain. The study examined the critical connection between the brain and pain for treating chronic pain. Specifically, they looked at the importance of pain attributions, which are people's beliefs about the underlying causes of their pain, to reduce chronic back pain severity.
Published Researchers 'bioprint' living brain cell networks in the lab (via sciencedaily.com) Original source
Researchers have successfully used 'bioinks' containing living nerve cells (neurons) to print 3D nerve networks that can grow in the laboratory and transmit and respond to nerve signals.
Published A quarter of people are undoing the benefits of healthy meals by unhealthy snacking (via sciencedaily.com) Original source
A quarter of people are undoing the benefits of healthy meals with unhealthy snacks, which increases the risk of strokes and cardiovascular disease.
Published Scrambler therapy may offer lasting relief for chronic pain, review paper suggests (via sciencedaily.com) Original source
Pain experts suggest that scrambler therapy, a noninvasive pain treatment, can yield significant relief for approximately 80% -- 90% of patients with chronic pain, and it may be more effective than another noninvasive therapy: transcutaneous electrical nerve stimulation (TENS).
Published Gene therapy treats chronic pain by dialing down sodium (via sciencedaily.com) Original source
Scientists identified the region where a protein regulates sodium ion channels, inserting the channel's genetic material into a virus to alleviate pain in cell and animal studies.
Published Researchers use the antidepressant tianeptine to manage chronic pain (via sciencedaily.com) Original source
Neuropathic pain is a debilitating condition estimated to affect as much as 10% of the global population. It results from a damaged or malfunctioning nervous system, stemming from diseases like diabetes, alcoholism, strokes, Parkinson's and other causes like spinal nerve compression, radiation and chemotherapy treatments. Management of neuropathic pain has been particularly challenging as currently prescribed drugs, such as anticonvulsants and antidepressants can have severe adverse effects, are not well-tolerated, take a longer time to work only help a subset of patients.
Published Global diet study challenges advice to limit high-fat dairy foods (via sciencedaily.com) Original source
Unprocessed red meat and whole grains can be included or left out of a healthy diet, according to a study conducted in 80 countries across all inhabited continents. Diets emphasizing fruit, vegetables, dairy (mainly whole-fat), nuts, legumes and fish were linked with a lower risk of cardiovascular disease (CVD) and premature death in all world regions. The addition of unprocessed red meat or whole grains had little impact on outcomes.
Published Not eating enough of these six healthy foods is associated with higher cardiovascular disease and deaths globally (via sciencedaily.com) Original source
Previous and similar research has focused on Western countries and diets that combined harmful, ultra-processed foods with nutrient-dense foods. This research was global in scope and focused on foods commonly considered to be healthy. Researchers derived a diet score from PHRI's ongoing, large-scale global Prospective Urban and Rural Epidemiological (PURE) study, then replicated that in five independent studies to measure health outcomes in different world regions and in people with and without prior CVD.