Showing 20 articles starting at article 1
Published Body's immune response may offer alternative approach to neuropathic pain therapies (via sciencedaily.com) Original source
In the midst of a global opioid epidemic, a team of scientists is exploring natural killer (NK) cells as an alternative treatment for neuropathic pain. Researchers gather existing evidence for the impact of NK cells in pain, pointing to their ability to prune the damaged nerve cells that may cause it. They urge the scientific community to explore biological mechanisms underlying NK cell activity to move towards a realistic pain therapy that is both effective and safe.
Published Innovative paper-like, battery-free, AI-enabled sensor for holistic wound monitoring (via sciencedaily.com) Original source
Scientists have invented a paper-like, battery-free, AI-enabled sensor patch -- PETAL -- for convenient and effective monitoring of wound recovery. This novel technology provides early warning of complications to improve wound care. The paper-like, battery-free PETAL sensor patch uses five colorimetric sensors to measure biomarkers in the wound within 15 mins. A proprietary AI algorithm quickly analyses the digital image of the sensor patch to determine wound healing status with an accuracy rate of 97%.
Published Study hints at how cancer immunotherapy can be safer (via sciencedaily.com) Original source
Cancer immunotherapy has revolutionized treatment of many forms of cancer by unleashing the immune system response against tumors. Immunotherapies that block checkpoint receptors like PD-1, proteins that limit the capacity of T cells to attack tumors, have become the choice for the treatment of numerous types of solid cancer. However, the introduction of PD-1-blocking agents can often result in T cells attacking healthy tissues in addition to cancer cells, causing severe, sometimes life-threatening, side effects that can blunt the benefits of immunotherapy. A new study reveals new insights into how PD-1 functions to maintain healthy tissues, findings that can help scientists predict, treat, or even prevent the side effects of PD-1 blocking immunotherapies.
Published Pregnancy hormone repairs myelin damage in MS mouse model (via sciencedaily.com) Original source
A new study has identified a treatment that could repair myelin in the cortex, undoing some of the damage caused by MS.
Published The IL-17 protein plays a key role in skin aging (via sciencedaily.com) Original source
A team of scientists has discovered that IL-17 protein plays a central role in skin aging. The study highlights an IL-17-mediated ageing process to an inflammatory state.
Published PAINTing a wound-healing ink into cuts with a 3D-printing pen (via sciencedaily.com) Original source
The body is pretty good at healing itself, though more severe wounds can require bandages or stitches. But researchers have now developed a wound-healing ink that can actively encourage the body to heal by exposing the cut to immune-system vesicles. The ink can be spread into a cut of any shape using a 3D-printing pen, and in mice, the technology nearly completely repaired wounds in just 12 days.
Published New type of drug candidate effectively accelerates wound healing in clinical study (via sciencedaily.com) Original source
Complicated, hard-to-heal wounds are a growing medical problem and there are currently only two drugs approved with proven efficacy. In a new study on humans, researchers show that treatment with a specific type of modified lactic acid bacteria works well and has a positive effect on the healing of wounds.
Published New chemical compound demonstrates potential in nerve regeneration (via sciencedaily.com) Original source
Recent research has identified a new compound that can stimulate nerve regeneration after injury, as well as protect cardiac tissue from the sort of damage seen in heart attack.
Published One step closer to developing a potentially ultraprotective sunscreen from our own melanin (via sciencedaily.com) Original source
Researchers have announced a major advance in understanding the fundamental structure of melanin and one of its components that turns light into heat, protecting the body from sun damage.
Published Non-antibiotic treatment for women with persistent acne shown to be effective (via sciencedaily.com) Original source
A team of researchers has shown that a cheap and readily available drug, used to treat high blood pressure, could help the thousands of women who suffer from persistent acne.
Published Neuropathic pain: The underlying mechanism and a potential therapeutic target are revealed in mice (via sciencedaily.com) Original source
Neuropathic pain -- abnormal hypersensitivity to stimuli -- is associated with impaired quality of life and is often poorly managed. Estimates suggest that 3 percent to 17 percent of adults suffer from neuropathic pain, including a quarter of people with diabetes and a third of people with HIV. Researchers report that a mechanism involving the enzyme Tiam1 in dorsal horn excitatory neurons of the spinal cord both initiates and maintains neuropathic pain. Moreover, they show that targeting spinal Tiam1 with anti-sense oligonucleotides injected into the cerebrospinal fluid effectively alleviated neuropathic pain hypersensitivity.
Published Researchers reveal an ancient mechanism for wound repair (via sciencedaily.com) Original source
The study is the first to identify a damage response pathway that is distinct from but parallel to the classical pathway triggered by pathogens.
Published How alcohol consumption contributes to chronic pain (via sciencedaily.com) Original source
A team showed how both alcohol intake and alcohol withdrawal can lead to increased pain and hypersensitivity.
Published Wearable patch can painlessly deliver drugs through the skin (via sciencedaily.com) Original source
A wearable patch applies painless ultrasonic waves to the skin, creating tiny channels that drugs can pass through.
Published The wound dressing that can reveal infection (via sciencedaily.com) Original source
A nanocellulose wound dressing that can reveal early signs of infection without interfering with the healing process has been developed.
Published Now you can be comfortable in your e-skin (via sciencedaily.com) Original source
Researchers have designed a cellulose nanofiber paper (nanopaper) that can be used as a substrate for on-skin electronics. The porous structure of the nanopaper means that it can conform and adhere to the skin well enough for effective signal transfer and allows moisture to pass through for breathability and comfort. It is hoped that the nanopaper can soon be used to acquire electrophysiological data, such as ECGs in the clinic.
Published How electricity can heal wounds three times as fast (via sciencedaily.com) Original source
Chronic wounds are a major health problem for diabetic patients and the elderly -- in extreme cases they can even lead to amputation. Using electric stimulation, researchers have developed a method that speeds up the healing process, making wounds heal three times faster.
Published Select cells 'home in on the skin like guided missiles' at birth to enhance immunity (via sciencedaily.com) Original source
Like deployment of an elite fighting team, localization of certain T cells to the skin is important at birth and for lifelong immunity, according to new research.
Published Genetic therapy corrects progressive muscle disorder in mice (via sciencedaily.com) Original source
Investigators recently used a targeted drug to restore muscle strength and correct myotonia in mice with myotonic dystrophy.
Published Students engineer socks for on-the-go neuropathy treatment (via sciencedaily.com) Original source
A wearable electrical-stimulation and vibration-therapy system designed by engineering students might be just what the doctor ordered for people experiencing foot pain and balance loss due to diabetic neuropathy.