Showing 20 articles starting at article 1
Published How pre- and postnatal B-12 vitamins improve breast milk vitamin B-12 levels, which supports infant brain development (via sciencedaily.com) Original source
According to a new study B-12 vitamins increase the presence of the micronutrient in mothers' breast milk, which is especially helpful in countries where it can be difficult to eat what is needed for the body to produce B-12 naturally.
Published Lost brain function restored in mice after stroke (via sciencedaily.com) Original source
Researchers have succeeded in restoring lost brain function in mouse models of stroke using small molecules that in the future could potentially be developed into a stroke recovery therapy.
Published Common headaches tied to neck inflammation (via sciencedaily.com) Original source
Researchers have identified objective evidence of how the neck muscles are involved in primary headaches, according to a new study.
Published Fat cells help repair damaged nerves (via sciencedaily.com) Original source
Damage to the body's peripheral nerves can cause pain and movement disorders. Researchers have recently investigated how damaged nerves can regenerate better. They found that fat tissue strongly supports the Schwann cells needed for repair during the healing process.
Published Repairing nerve cells after injury and in chronic disease (via sciencedaily.com) Original source
Researchers discovered a mechanism for repairing damaged nerves during peripheral neuropathy in mice, wherein the protein Mitf orchestrates nerve repair after both trauma-induced and chronic nerve damage conditions, like Charcot Marie Tooth disease. Their findings may inspire novel therapeutics that bolster repair function and heal peripheral neuropathy -- even in hereditary and developmental cases.
Published Novel molecular mechanisms in the early development of diabetes mellitus (via sciencedaily.com) Original source
Researchers conducted a gene expression analysis at the single-cell level on pancreatic islets from prediabetic and diabetic mouse models. Analysis results revealed upregulation of Anxa10 expression in pancreatic beta cells during the early phases of diabetes, attributed to elevated blood glucose levels. This elevated Anxa10 expression was found to influence intracellular calcium homeostasis, leading to a reduction in insulin secretory capacity.
Published Getting to the root of visceral gut pain (via sciencedaily.com) Original source
Researchers have uncovered a reason that may explain why visceral pain is so common in conditions like irritable bowel syndrome. This understanding could inspire new and better ways to alleviate that pain.
Published Urban environmental exposures drive increased breast cancer incidence (via sciencedaily.com) Original source
An analysis of breast cancer showed that the state’s urban counties had higher overall incidences of disease than rural counties, especially at early stages upon diagnosis.
Published New compound outperforms pain drug by indirectly targeting calcium channels (via sciencedaily.com) Original source
A compound -- one of 27 million screened in a library of potential new drugs -- reversed four types of chronic pain in animal studies, according to new research. The small molecule, which binds to an inner region of a calcium channel to indirectly regulate it, outperformed gabapentin without troublesome side effects, providing a promising candidate for treating pain.
Published Side-effect avoiding treatment shows early promise against breast cancer in mice (via sciencedaily.com) Original source
New experimental evidence suggests that substances known as narrow-spectrum Wnt signaling inhibitors -- which could have fewer side effects than other related substances -- are capable of suppressing the growth of breast cancer tumors in mice.
Published Disturbances in sensory neurons may alter transient pain into chronic pain (via sciencedaily.com) Original source
Researchers have identified that a transient inflammatory pain causes mitochondrial and redox changes in sensory neurons that persist beyond pain resolution. These changes appear to predispose to a failure in resolution of pain caused by a subsequent inflammation. Additionally, targeting the cellular redox balance prevents and treats chronic inflammatory pain in rodents.
Published Higher risk of breast cancer in women with false positive mammography result (via sciencedaily.com) Original source
Women who receive a false positive mammography result are more likely to develop breast cancer over the subsequent 20 years, report researchers. The risk is highest for women aged between 60 and 75 and who have low breast density.
Published COVID vaccination in female, male partners does not increase risk of miscarriage, study finds (via sciencedaily.com) Original source
A new study provides deeper insight into the safety of COVID-19 vaccines for people planning to become pregnant. The study found no increased risk of early or late miscarriage as a result of male or female partners getting a COVID-19 vaccine prior to conceiving.
Published Lab unlocks keys to alcohol withdrawal headache (via sciencedaily.com) Original source
Researchers have discovered mechanisms by which specific cells are activated in alcohol withdrawal-induced headache. The research may benefit further studies of various substance use disorder mechanisms including withdrawal. It may be possible to develop a small-molecule drug therapy to inhibit interactions, resulting in fewer pain signals during alcohol withdrawal.
Published Cutting-edge imaging sheds new light on cells that break down bone (via sciencedaily.com) Original source
Imaging technology shows that bone-resorbing osteoclasts gather in distinct pockets, leading to new insights for osteoporosis and cancer treatment.
Published Researchers uncover mechanism that links NAD+ to fertility problems (via sciencedaily.com) Original source
A woman's fertility normally decreases by her late 30s with reproductive function eventually ceasing at menopause. It is known that a small molecule called nicotinamide adenine dinucleotide (NAD+) plays a critical role in this decline, and scientists have revealed how this happens and have identified potential new approaches to enhance reproductive longevity.
Published Women living in more walkable neighborhoods have lower rates of obesity-related cancers (via sciencedaily.com) Original source
Residing in a more walkable neighborhood protects against the risk of overall obesity-related cancers in women, specifically postmenopausal breast cancer, but also ovarian cancer, endometrial cancer, and multiple myeloma, according to a new study. Obesity has been linked to increased risk for 13 types of cancer in women, and physical activity, independent of body size, lowers risk for some of these cancers. Until now long-term studies of neighborhood walkability and risk for obesity-related cancer were limited.
Published Is a longer reproductive lifespan good for your brain? (via sciencedaily.com) Original source
People with a higher cumulative estrogen exposure throughout their life may have a lower risk of cerebral small vessel disease, according to a new study.
Published New study provides evidence for more effective brain-based treatment of chronic back pain (via sciencedaily.com) Original source
A new study may provide key answers to how to help people experiencing chronic back pain. The study examined the critical connection between the brain and pain for treating chronic pain. Specifically, they looked at the importance of pain attributions, which are people's beliefs about the underlying causes of their pain, to reduce chronic back pain severity.
Published Wearable patch wirelessly monitors estrogen in sweat (via sciencedaily.com) Original source
A new sensor may make it easier for women to monitor their estradiol, which plays a role in health and fertility.