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Categories: Chronic Fatigue Syndrome, Irritable Bowel Syndrome

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     (via sciencedaily.com)     Original source 

Changing the structure of a dietary fiber commonly found in a range of food products has been found to promote healthy gut bacteria and reduce gas formation, a finding that could help people with intolerances to fiber and irritable bowel conditions.

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Researchers have found differences in the gut microbiomes of people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) compared to healthy controls. Findings from two studies add to growing evidence that connects disruptions in the gut microbiome, the complete collection of bacteria, viruses, and fungi that live in our gastrointestinal system, to ME/CFS.

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People with irritable bowel syndrome (IBS) have lower bacterial diversity in the intestine than do healthy people, according to a team of investigators. The investigators believe that theirs is the first analysis to find a clear association between IBS and reduced diversity in the microbiota of the gut.

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A research group recorded the autonomic nervous system activity in patients with irritable bowel syndrome (IBS) and healthy subjects using a wearable device and a proprietary smartphone application to record daily life events such as defecation and sleep. As a result, they found that sympathetic nervous system activity was activated in IBS patients from 2 minutes before defecation and continued until 9 minutes after defecation. Further research is expected to improve the quality of life of IBS patients and elucidate the pathophysiology.

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Targeting a receptor responsible for our sense of touch and temperature, which researchers have now found to be present in our colon, could provide a new avenue for treating chronic pain associated with gastrointestinal disorders such as irritable bowel syndrome. A team examining the colon identified the presence of Piezo2, the subject of the 2021 Nobel Prize in Physiology or Medicine, now known to be responsible for sensing light touch on our skin.

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A new theory suggests irritable bowel syndrome (IBS), the most common gastrointestinal disorder, may be caused by gravity. An expert explains that IBS -- and many other conditions -- could result from the body's inability to manage gravity.

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Nearly 1 in 7 Americans experience bloating on a weekly basis, and most aren't seeking professional care for it, according to a new study.

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Inflammatory bowel disease is a risk factor for giving birth preterm even when in apparent disease remission, a new study shows. If corroborated, the results may eventually affect recommendations for women with ulcerative colitis who tries to conceive.

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Since the beginning of the pandemic, SARS-CoV-2 has been suspected of causing chronic fatigue syndrome (ME/CFS). A well-controlled study has now shown that, even after mild COVID-19, a subset of patients will develop symptoms which meet the diagnostic criteria for ME/CFS. Their findings also describe a second subset of post-COVID patients with similar symptoms. Differences in laboratory results between these groups may indicate differences in underlying mechanisms.

     (via sciencedaily.com)     Original source 

The culprit is what has now been named Klebsiella aerogenes, the McMaster-Queen (MQ) strain, identified in up to 25 per cent of gut microbiota samples from patients with IBS. Researchers examined stool microbiota samples from both Canadian and American patient cohorts.

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Researchers have uncovered how post-viral fatigue syndromes, including Long COVID, become life-changing diseases and why patients suffer frequent relapses.

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Dormant herpesviruses induce their reactivation via a previously unknown cellular mechanism mediated by a viral microRNA.

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In a new article, experts highlight what is currently known about the effects of SARS-CoV-2 on the brain, the importance of increased research into the underlying causes of Long COVID and possible ways to treat its symptoms.

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Many IBS sufferers avoid certain types of food and often exclude gluten. However, a large new study does not show a relationship between high intake of gluten and increased IBS symptoms. The researchers did find that a certain type of carbohydrate called 'fodmaps' can aggravate intestinal problems, however, the overall results indicate that they also have less influence than previously thought.

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Many long-haul COVID-19 patients have chronic fatigue syndrome and other breathing issues months after their initial COVID-19 diagnosis, according to a new study.

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For patients who have irritable bowel syndrome (IBS), the condition is literally a pain in the gut. Chronic -- or long-term -- abdominal pain is common, and there are currently no effective treatment options for this debilitating symptom. In a new study, researchers identify a new potential source of relief: a molecule derived from spider venom. In experiments with mice, they found that one dose could stop symptoms associated with IBS pain.

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In a randomized clinical trial, researchers found participants with moderate to severe irritable bowel syndrome (IBS) who were knowingly treated with a pharmacologically inactive pill -- referred to as an honest or open-label placebo -- reported clinically meaningful improvements in their IBS symptoms.

     (via sciencedaily.com)     Original source 

Researchers have identified the biological mechanism that explains why some people experience abdominal pain when they eat certain foods. The finding paves the way for more efficient treatment of irritable bowel syndrome and other food intolerances. The study was carried out in mice and humans.

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Preclinical studies find that an innovative bilayered capsule can overcome current challenges for delivering drugs to the colon. The findings suggest a new solution for relieving abdominal pain associated with IBS-C.

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Researchers have detected a connection between Brachyspira, a genus of bacteria in the intestines, and IBS -- especially the form that causes diarrhea. Although the discovery needs confirmation in larger studies, there is hope that it might lead to new remedies for many people with irritable bowel syndrome.