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Categories: Chronic Fatigue Syndrome, Schizophrenia

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Psychology Research Schizophrenia
Published

Two key brain systems are central to psychosis      (via sciencedaily.com)     Original source 

When the brain has trouble filtering incoming information and predicting what's likely to happen, psychosis can result, research shows.

Healthy Aging Psychology Research Schizophrenia
Published

Reverse effects of trauma? Older brain cells linger unexpectedly before their death      (via sciencedaily.com)     Original source 

Researchers report that mature oligodendrocytes -- the central nervous system cells critical for brain function -- cling to life following a fatal trauma for much, much longer than scientists knew. The findings suggest a new pathway for efforts to reverse or prevent the damage that aging and diseases such as multiple sclerosis cause to these important cells.

Healthy Aging Schizophrenia
Published

Schizophrenia and aging may share a common biological basis      (via sciencedaily.com)     Original source 

Researchers have uncovered a strikingly similar suite of changes in gene activity in brain tissue from people with schizophrenia and from older adults. These changes suggest a common biological basis for the cognitive impairment often seen in people with schizophrenia and in the elderly.

Chronic Fatigue Syndrome Chronic Illness Today's Healthcare
Published

Chronic fatigue syndrome: Number of patients is expected to double due to long-term effects of the COVID-19 pandemic      (via sciencedaily.com)     Original source 

The number of ME/CFS patients is expected to rise drastically due to long-term effects of the COVID-19 pandemic. Scientists have now identified possible biomarkers that could improve the diagnosis and treatment of long-lasting and debilitating fatigue.

Children's Health Mental Health Research Psychology Research Schizophrenia
Published

Bullied teens' brains show chemical change associated with psychosis      (via sciencedaily.com)     Original source 

Researchers have found that adolescents being bullied by their peers are at greater risk of the early stages of psychotic episodes and in turn experience lower levels of a key neurotransmitter in a part of the brain involved in regulating emotions. The finding suggests that this neurotransmitter may be a potential target for pharmaceutical interventions aimed at reducing the risk of psychotic disorders.

Healthy Aging Neuropathy Psychology Research Schizophrenia
Published

Firing nerve fibers in the brain are supplied with energy on demand      (via sciencedaily.com)     Original source 

To rapidly transmit electrical signals in the brain, the long nerve fibers are insulated by specialized cells called oligodendrocytes. These cells also respond to the electrical signals of active nerve fibers and provide them with energy on demand, as researchers have discovered. If this process, regulated by potassium, is disabled in mice, the nerve fibers are severely damaged as the animals age -- resembling the defects of neurodegenerative diseases.

Schizophrenia Today's Healthcare
Published

Vigilant monitoring is needed to manage cardiac risks in patients using antipsychotics, doctors say      (via sciencedaily.com)     Original source 

The use of the antipsychotic drugs quetiapine and haloperidol is associated with an increased risk of ventricular arrhythmias and sudden cardiac death (SCD) caused by drug-induced QT prolongation, reports a new study. Caution is advised to manage cardiac risks in patients prescribed these medications, the authors of the study and an accompanying editorial say.

Chronic Illness Psychology Research Schizophrenia
Published

Study reveals function of little-understood synapse in the brain      (via sciencedaily.com)     Original source 

New research for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications for conditions ranging from multiple sclerosis to Alzheimer's disease, to a type of brain cancer known as glioma. Neuroscientists focused on the synapse connecting neurons to a non-neuronal cell, known as oligodendrocyte precursor cells. OPCs can differentiate into oligodendrocytes, which produce a sheath around nerves known as myelin. Myelin is the protective sheath covering each nerve cell's axon -- the threadlike portion of a cell that transmits electrical signals between cells.

Schizophrenia Today's Healthcare
Published

Clinical predictive models created by AI are accurate but study-specific, researchers find      (via sciencedaily.com)     Original source 

Scientists were able to show that statistical models created by artificial intelligence (AI) predict very accurately whether a medication responds in people with schizophrenia. However, the models are highly context-dependent and cannot be generalized.

Schizophrenia Today's Healthcare
Published

Quest for personalized medicine hits a snag      (via sciencedaily.com)     Original source 

The quest for personalized medicine, a medical approach in which practitioners use a patient's unique genetic profile to tailor individual treatment, has emerged as a critical goal in the health care sector. But a new study shows that the mathematical models currently available to predict treatments have limited effectiveness.

Child Development Mental Health Research Schizophrenia
Published

Unravelling the association between neonatal proteins and adult health      (via sciencedaily.com)     Original source 

Scientists studied two complement components that are important parts of the immune system and are linked to schizophrenia and autoimmune disorders. They studied the link between two protein concentrations -- C3 and C4 -- in over 68,000 newborn babies and the risk of developing six mental disorders later in life.

Psychology Research Schizophrenia
Published

An unexpected link between 2 schizophrenia risk proteins      (via sciencedaily.com)     Original source 

The discovery of a physical interaction between two proteins in brain cells that can be traced in mice to control of movement, anxiety and memory could one day open the door to development of new schizophrenia treatment strategies, researchers say.

Birth Defects Schizophrenia
Published

New clues to early development of schizophrenia      (via sciencedaily.com)     Original source 

Schizophrenia is a severe neuropsychiatric disease that remains poorly understood and treated. Schizophrenia onset is typically in adolescence or early adulthood, but its underlying causes are thought to involve neurodevelopmental abnormalities. Because human prenatal and postnatal brain tissue is exceedingly difficult to procure and therefore study, researchers have had limited opportunities to identify early disease mechanisms, especially during the critical prenatal period. Now, a pair of studies use new technology to study schizophrenia in models of early human brain development.

Psychology Research Schizophrenia
Published

Brain connectivity is disrupted in schizophrenia      (via sciencedaily.com)     Original source 

Schizophrenia, a neurodevelopmental disorder that features psychosis among its symptoms, is thought to arise from disorganization in brain connectivity and functional integration. Now, a new study finds differences in functional brain connectivity in people with and without psychosis and schizophrenia that could help researchers understand the neural underpinnings of this disease.

Child Development Psychology Research Schizophrenia
Published

AI language models could help diagnose schizophrenia      (via sciencedaily.com)     Original source 

Scientists have developed new tools, based on AI language models, that can characterize subtle signatures in the speech of patients diagnosed with schizophrenia.

Schizophrenia
Published

Scientists take next big step in understanding genetics of schizophrenia      (via sciencedaily.com)     Original source 

Scientists are figuring out which of the 5,000 variants associated with schizophrenia have an actual causal effect in the development of the condition that affects millions of people worldwide.

Chronic Fatigue Syndrome Chronic Illness
Published

Women more severely affected by chronic fatigue syndrome      (via sciencedaily.com)     Original source 

Women with ME/CFS tend to have more symptoms and co-occurring conditions than men, according to initial results from the world's largest study of the disease. It has long been known that women are more likely to have ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) but the DecodeME study has shown for the first time how their experience differs from men.

Birth Defects Schizophrenia
Published

Schizophrenia genetic risk factor impairs mitochondrial function      (via sciencedaily.com)     Original source 

Researcher discovers possible link of mitochondrial function to the development of schizophrenia.

Schizophrenia
Published

New neuroimaging approach could improve diagnosis of schizophrenia      (via sciencedaily.com)     Original source 

New research has identified age-related changes in brain patterns associated with the risk for developing schizophrenia. The discovery could help clinicians identify the risk for developing mental illness earlier and improve treatment options.