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Categories: Crohn's Disease, Thyroid Disease

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Crohn's Disease Today's Healthcare
Published

Treating newly-diagnosed Crohn's patients with advanced therapy leads to dramatic improvements in outcomes      (via sciencedaily.com)     Original source 

A large-scale clinical trial of treatment strategies for Crohn's disease has shown that offering early advanced therapy to all patients straight after diagnosis can drastically improve outcomes, including by reducing the number of people requiring urgent abdominal surgery for treatment of their disease by ten-fold.

Chronic Illness Crohn's Disease Mental Health Research Today's Healthcare
Published

Mood interventions may reduce inflammation in Crohn's and Colitis      (via sciencedaily.com)     Original source 

New research reveals that interventions which improve mood can reduce levels of inflammation in people with inflammatory bowel disease by 18 per cent, compared to having no mood intervention.

Thyroid Disease
Published

Novel PET tracer enhances lesion detection in medullary thyroid cancer, offers potential for targeted therapy      (via sciencedaily.com)     Original source 

A newly developed PET imaging agent has been found to be effective in identifying medullary thyroid cancer (MTC) in preclinical and clinical studies. The results of the studies indicate that the PET imaging agent may be a promising theranostic candidate for clinical use.

Chronic Illness Crohn's Disease
Published

Researchers reveal prevalence of persistent symptoms in patients with microscopic colitis      (via sciencedaily.com)     Original source 

A new study examines how multiple factors contribute to the miscommunication and understanding of the digestive disease, microscopic colitis.

Chronic Illness Hormone Disorders Thyroid Disease
Published

Anti-rheumatic drugs could prevent thyroid disease      (via sciencedaily.com)     Original source 

Anti-rheumatic drugs used for rheumatoid arthritis might prevent the development of autoimmune thyroid disease, according to a new observational study.

Chronic Illness Crohn's Disease Today's Healthcare
Published

Comprehensive guideline on using biomarkers for monitoring Crohn's disease      (via sciencedaily.com)     Original source 

New AGA guideline outlines reliable blood and stool tests to monitor inflammation that can reduce how often patients need invasive endoscopy. 

Crohn's Disease Diet and Weight Loss Nutrition
Published

Early life exposure to broccoli sprouts protects against colitis in inflammatory bowel disease      (via sciencedaily.com)     Original source 

High fiber diets, like those that include broccoli sprouts or other cruciferous vegetables, may reduce disease symptoms and improve quality of life in patients with inflammatory bowel disease (IBD).

Chronic Illness Crohn's Disease
Published

Body changes up to eight years before inflammatory bowel disease diagnosis      (via sciencedaily.com)     Original source 

Researchers have shown that changes can be detected in blood tests up to eight years before a diagnosis of Crohn's disease and up to three years before a diagnosis of ulcerative colitis.

Chronic Illness Crohn's Disease Irritable Bowel Syndrome
Published

Risk of serious infection even in low-active IBD      (via sciencedaily.com)     Original source 

Inflammatory bowel disease (IBD) is an independent risk factor for serious infection, even at very low levels of gastrointestinal inflammation.

Crohn's Disease
Published

A promising target to fight inflammatory bowel diseases      (via sciencedaily.com)     Original source 

Inflammatory bowel diseases (IBDs), such as Crohn's disease or ulcerative colitis, arise when there is a dysregulation of cell signalling pathways, leading to a chronic inflammatory response. The gut inflammatory response relies on a chain reaction involving several molecules, including RIPK2 -- known to be a good target for inhibitors treating IBDs. Researchers from the Cusack group at EMBL Grenoble have provided new insights into the interactions between RIPK2 and XIAP, another molecule involved in the inflammatory response, during the downstream chain reaction. These results, when taken together with previous structural biology studies on RIPK2, offer valuable information for the development of therapeutics to treat inflammatory bowel diseases.

Crohn's Disease
Published

Fungi used in food production could lead to new probiotics      (via sciencedaily.com)     Original source 

According to a new study, 2 fungi used to produce food products have potential probiotic effects on gut inflammation.

Thyroid Disease Today's Healthcare
Published

Certain per- and polyfluoroalkyl 'forever chemicals' identified as potential risk factor for thyroid cancer      (via sciencedaily.com)     Original source 

Researchers have discovered a link between certain per- and polyfluoroalkyl substances (PFAS) and an increased risk for thyroid cancer.

Children's Health Crohn's Disease Skin Care Today's Healthcare
Published

Inflammatory bowel disease linked to atopic dermatitis      (via sciencedaily.com)     Original source 

Adults with atopic dermatitis (AD) have a 34 percent increased risk of developing new-onset inflammatory bowel disease (IBD) compared with individuals who do not have the skin condition, and children have a 44 percent increased risk, according to a new study.

Crohn's Disease
Published

Developing a less invasive test for inflammatory bowel disease      (via sciencedaily.com)     Original source 

Millions of Americans have inflammatory bowel disease (IBD), which occurs in one of two forms: Crohn's disease or ulcerative colitis. Though the two have similar symptoms, they require different treatment strategies, and tests to distinguish between them are invasive. Researchers now show that chains of sugar molecules are tacked onto antibodies differently in patients with the diseases, which could someday lead to a simple blood-based diagnostic test.

Children's Health Crohn's Disease
Published

Neonatal stem cells from the heart could treat Crohn's disease      (via sciencedaily.com)     Original source 

Research found that direct injection of neonatal mesenchymal stem cells, derived from heart tissue discarded during surgery, reduces intestinal inflammation and promotes wound healing in a mouse model of Crohn's disease-like ileitis, an illness marked by chronic intestinal inflammation and progressive tissue damage. The study offers a promising new and alternative treatment approach that avoids the pitfalls of current Crohn's disease medications, including diminishing effectiveness, severe side effects and increased risk of gastrointestinal dysfunction.

Crohn's Disease
Published

Nanomedicine for treating inflammatory bowel disease      (via sciencedaily.com)     Original source 

Chronic inflammatory bowel disease (IBD), such as Crohn's disease and ulcerative colitis, is on the rise worldwide. The benefits of current medications are limited by problematic side effects. A research team has now introduced a new method of treatment. It is based on nanoparticles that mimic a special carbohydrate layer (glycocalyx) located on inflamed bowel cells, and which trigger anti-inflammatory effects in the diseased sites in the intestine.

Crohn's Disease Obesity
Published

Scientists link genes to diet in inflammatory bowel disease      (via sciencedaily.com)     Original source 

A study of the genetic variation that makes mice more susceptible to bowel inflammation after a high-fat diet has identified candidate genes which may drive inflammatory bowel disease (IBD) in humans.

Crohn's Disease
Published

Pathogenic bacteria use a sugar in the intestinal mucus layer to infect the gut, study shows      (via sciencedaily.com)     Original source 

A new study shows the sugar sialic acid, which makes up part of the protective intestinal mucus layer, fuels disease-causing bacteria in the gut. The findings suggest a potential treatment target for intestinal bacterial infections and a range of chronic diseases linked to gut bacteria, including inflammatory bowel disease (IBD), celiac disease, irritable bowel syndrome and short bowel syndrome.

Crohn's Disease Women's Health - General
Published

Helping 'good' gut bacteria and clearing out the 'bad' -- all in one treatment      (via sciencedaily.com)     Original source 

Probiotics can help maintain a healthy gut microbiome or restore populations of 'good bacteria' after a heavy course of antibiotics. But now, they could also be used as an effective treatment strategy for certain intestinal diseases, such as Crohn's disease. Researchers have developed a microgel delivery system for probiotics that keeps 'good' bacteria safe while actively clearing out 'bad' ones. In mice, the system treated intestinal inflammation without side effects.

Hormone Disorders Thyroid Disease
Published

Exposure to dioxins can worsen thyroid function      (via sciencedaily.com)     Original source 

Exposure to dioxins can negatively impact thyroid function, according to a study presented Thursday at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill.