Showing 20 articles starting at article 1
Published Comprehensive guideline on using biomarkers for monitoring Crohn's disease (via sciencedaily.com) Original source
New AGA guideline outlines reliable blood and stool tests to monitor inflammation that can reduce how often patients need invasive endoscopy.
Published High levels of maternal stress during pregnancy linked to children's behavior problems (via sciencedaily.com) Original source
Children whose mothers are highly stressed, anxious or depressed during pregnancy may be at higher risk for mental health and behavior issues during their childhood and teen years, according to new research.
Published Early-life stress changes more genes in brain than a head injury (via sciencedaily.com) Original source
A surprising thing happened when researchers began exploring whether early-life stress compounds the effects of a childhood head injury on health and behavior later in life: In an animal study, stress changed the activation level of many more genes in the brain than were changed by a bump to the head.
Published Early life exposure to broccoli sprouts protects against colitis in inflammatory bowel disease (via sciencedaily.com) Original source
High fiber diets, like those that include broccoli sprouts or other cruciferous vegetables, may reduce disease symptoms and improve quality of life in patients with inflammatory bowel disease (IBD).
Published Body changes up to eight years before inflammatory bowel disease diagnosis (via sciencedaily.com) Original source
Researchers have shown that changes can be detected in blood tests up to eight years before a diagnosis of Crohn's disease and up to three years before a diagnosis of ulcerative colitis.
Published Why we don't all develop posttraumatic stress disorder after trauma (via sciencedaily.com) Original source
Researchers show why only a subset of individuals exposed to trauma develop posttraumatic stress disorder (PTSD). The research, centered on the body's stress hormone response, could pave the way for more targeted treatments for PTSD.
Published New clues to the mechanism behind treatment-resistant depression (via sciencedaily.com) Original source
Major depressive disorder (MDD) is a widespread mental health condition that for many is disabling. It has long been appreciated that MDD has genetic as well as environmental influences. In a new study researchers identify a gene that interacted with stress to mediate aspects of treatment-resistant MDD in an animal model.
Published Risk of serious infection even in low-active IBD (via sciencedaily.com) Original source
Inflammatory bowel disease (IBD) is an independent risk factor for serious infection, even at very low levels of gastrointestinal inflammation.
Published A promising target to fight inflammatory bowel diseases (via sciencedaily.com) Original source
Inflammatory bowel diseases (IBDs), such as Crohn's disease or ulcerative colitis, arise when there is a dysregulation of cell signalling pathways, leading to a chronic inflammatory response. The gut inflammatory response relies on a chain reaction involving several molecules, including RIPK2 -- known to be a good target for inhibitors treating IBDs. Researchers from the Cusack group at EMBL Grenoble have provided new insights into the interactions between RIPK2 and XIAP, another molecule involved in the inflammatory response, during the downstream chain reaction. These results, when taken together with previous structural biology studies on RIPK2, offer valuable information for the development of therapeutics to treat inflammatory bowel diseases.
Published Fungi used in food production could lead to new probiotics (via sciencedaily.com) Original source
According to a new study, 2 fungi used to produce food products have potential probiotic effects on gut inflammation.
Published Study indicates possible link between chronic stress and Alzheimer's disease (via sciencedaily.com) Original source
Researchers have published a study that addresses possible associations between chronic stress, mild cognitive impairment and Alzheimer’s disease. The study shows how people aged between 18 and 65 with a previous diagnosis of chronic stress and depression were more likely than other people to be diagnosed with mild cognitive impairment or Alzheimer’s disease.
Published Posttraumatic brain activity predicts resilience to PTSD (via sciencedaily.com) Original source
After a traumatic experience, most people recover without incident, but some people -- between 2% and 10% -- develop posttraumatic stress disorder (PTSD), a mental health condition that can cause debilitating symptoms of anxiety due to emotional dysregulation. PTSD symptoms are present in up to 40% of trauma survivors in the acute aftermath of trauma, but full-blown PTSD develops in only a small subset of cases. Early identification of those at risk is critical for both early treatment and possible prevention.
Published Inflammatory bowel disease linked to atopic dermatitis (via sciencedaily.com) Original source
Adults with atopic dermatitis (AD) have a 34 percent increased risk of developing new-onset inflammatory bowel disease (IBD) compared with individuals who do not have the skin condition, and children have a 44 percent increased risk, according to a new study.
Published Your body's own cannabinoid molecules calm you during stress (via sciencedaily.com) Original source
When you're under stress, your brain may release its own cannabinoid molecules to calm you, activating the same brain receptors as THC derived from cannabis plants. But the brain activity regulated by these cannabinoid molecules were not well known. A new study in mice has discovered a key emotional brain center, the amygdala, releases cannabinoid molecules under stress that dampen the incoming stress alarm from the hippocampus, a memory and emotion center in the brain. The finding may reveal novel therapeutic targets for the treatment of stress-related disorders.
Published Developing a less invasive test for inflammatory bowel disease (via sciencedaily.com) Original source
Millions of Americans have inflammatory bowel disease (IBD), which occurs in one of two forms: Crohn's disease or ulcerative colitis. Though the two have similar symptoms, they require different treatment strategies, and tests to distinguish between them are invasive. Researchers now show that chains of sugar molecules are tacked onto antibodies differently in patients with the diseases, which could someday lead to a simple blood-based diagnostic test.
Published Active children are more resilient (via sciencedaily.com) Original source
The school year has hardly begun and the first exams are already approaching. According to findings by researchers from the University of Basel, school children cope better with the stress if they get plenty of daily exercise.
Published Stress and insomnia linked to irregular heart rhythms after menopause (via sciencedaily.com) Original source
A study of more than 83,000 questionnaires by women ages 50-79, found more than 25% developed irregular heart rhythms, known as atrial fibrillation, which may increase their risk for stroke and heart failure.
Published Neonatal stem cells from the heart could treat Crohn's disease (via sciencedaily.com) Original source
Research found that direct injection of neonatal mesenchymal stem cells, derived from heart tissue discarded during surgery, reduces intestinal inflammation and promotes wound healing in a mouse model of Crohn's disease-like ileitis, an illness marked by chronic intestinal inflammation and progressive tissue damage. The study offers a promising new and alternative treatment approach that avoids the pitfalls of current Crohn's disease medications, including diminishing effectiveness, severe side effects and increased risk of gastrointestinal dysfunction.
Published Nanomedicine for treating inflammatory bowel disease (via sciencedaily.com) Original source
Chronic inflammatory bowel disease (IBD), such as Crohn's disease and ulcerative colitis, is on the rise worldwide. The benefits of current medications are limited by problematic side effects. A research team has now introduced a new method of treatment. It is based on nanoparticles that mimic a special carbohydrate layer (glycocalyx) located on inflamed bowel cells, and which trigger anti-inflammatory effects in the diseased sites in the intestine.
Published High-quality sleep promotes resilience to depression and anxiety (via sciencedaily.com) Original source
Research has shown quality sleep can help bolster resilience to depression and anxiety.