Showing 20 articles starting at article 1
Published Study sets new standard for graft-versus-host disease prevention after stem cell transplant (via sciencedaily.com) Original source
Clinicians have a new standard for graft-versus-host disease (GVHD) prevention after allogeneic hematopoietic stem cell transplantation, according to results from a phase III study. The new standard is more effective at preventing GVHD and came with less side effects, compared with the current gold standard.
Published Pain not perceived in the same way in people with Alzheimer's Disease (via sciencedaily.com) Original source
New research has found that in a mouse model mimicking Alzheimer's Disease (AD) pain signals are not processed in the same way as in healthy mice.
Published Omega-3 fatty acids linked to slower decline in ALS (via sciencedaily.com) Original source
People with amyotrophic lateral sclerosis (ALS) who eat more foods high in certain omega-3 fatty acids like flaxseed oil, walnuts, canola oil and pumpkin seeds may have a slower physical decline from the disease and may have a slightly extended survival. Researchers also found an omega-6 fatty acid may be beneficial. The study does not prove that these omega fatty acids slow decline of ALS or extend survival; it only shows an association.
Published Blood pressure drug could prevent post-traumatic headaches (via sciencedaily.com) Original source
A study has shown that prazosin, a drug used to treat high blood pressure, can prevent post-traumatic headaches.
Published New findings show mitochondrial DNA fragments in blood as important biomarkers for aging and inflammation (via sciencedaily.com) Original source
In an eight-year study of more than 600 community-dwelling older adults, researchers say they have further linked levels of cell-free DNA (DNA fragments resulting from cell death) circulating in the blood to chronic inflammation and frailty. The study is novel and expands on previous work, the investigators say, because it focused on mitochondrial DNA rather than solely genomic DNA, as previously reported.
Published Helping 'good' gut bacteria and clearing out the 'bad' -- all in one treatment (via sciencedaily.com) Original source
Probiotics can help maintain a healthy gut microbiome or restore populations of 'good bacteria' after a heavy course of antibiotics. But now, they could also be used as an effective treatment strategy for certain intestinal diseases, such as Crohn's disease. Researchers have developed a microgel delivery system for probiotics that keeps 'good' bacteria safe while actively clearing out 'bad' ones. In mice, the system treated intestinal inflammation without side effects.
Published What role does alternative splicing play in neurodegenerative disease? (via sciencedaily.com) Original source
Scientists have written a review to discuss emerging research and evidence of the roles of alternative splicing defects in major neurodegenerative diseases. They also summarize the latest advances in RNA-based therapeutic strategies to target these disorders.
Published Researchers uncover why light-to-moderate drinking is tied to better heart health (via sciencedaily.com) Original source
A new study offers an explanation for why light-to-moderate alcohol consumption may be associated with lower risk of heart disease. For the first time, researchers found that alcohol, in light to moderate quantities, was associated with long-term reductions in stress signaling in the brain.
Published New study links contraceptive pills and depression (via sciencedaily.com) Original source
Women who used combined contraceptive pills were at greater risk of developing depression than women who did not, according to a new study. Contraceptive pills increased women's risk by 73 per cent during the first two years of use.
Published New research identifies cells linking chronic psychological stress to inflammatory bowel disease (via sciencedaily.com) Original source
For the first time, cells involved with the communication between stress responses in the brain and inflammation in the gastrointestinal (GI) tract have been identified in animal models. Glial cells, which support neurons, communicate stress signals from the central nervous system (CNS) to the semi-autonomous nervous system within the gastrointestinal (GI) tract, called the enteric nervous system (ENS). These psychological stress signals can cause inflammation and exacerbate symptoms of inflammatory bowel disease (IBD).
Published Sea cucumbers: The marine delicacy that can deter diabetes (via sciencedaily.com) Original source
They're a marine delicacy loved across Asia, but the humble sea cucumber is also proving to be a key ingredient in preventing diabetes, according to new research.
Published Poorly insulated nerve cells promote Alzheimer's disease in old age (via sciencedaily.com) Original source
Researchers have shown that defective myelin actively promotes disease-related changes in Alzheimer's disease.
Published Parkinson's disease drug ropinirole safely slowed the progression of ALS for over 6 months in a clinical trial (via sciencedaily.com) Original source
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a fatal motor neuron disease that causes people to gradually lose control of their muscles. There is no cure, and current treatments focus on reducing symptoms and providing supportive care. Researchers now show in an early clinical trial that the Parkinson's disease drug ropinirole is safe to use in ALS patients and delayed disease progression by 27.9 weeks on average.
Published Engineers report low-cost human biomarker sensor designs (via sciencedaily.com) Original source
Researchers have developed a low-cost, RNA-based technology to detect and measure biomarkers, which can help decode the body's physiology. The presence of protein biomarkers can indicate chronic or acute conditions, from arthritis to cancer to bacterial infections, for which conventional tests can cost anywhere from $100 to upwards of $1,000. The new technology can perform the same measurement for about a dollar.
Published Obesity increases risk of mental disorders throughout life (via sciencedaily.com) Original source
Being obese significantly increases the chances of also developing mental disorders. This applies to all age groups, with women at higher risk than men for most diseases.
Published A student's poor eating habits can lead to a lifetime of illness (via sciencedaily.com) Original source
A researcher is cautioning that a person's poor eating habits established during post-secondary studies can contribute to future health issues including obesity, respiratory illnesses and depression.
Published In 2050, over 800 million people globally estimated to be living with back pain (via sciencedaily.com) Original source
Study estimates there will be over 800 million cases of low back pain in 2050, a 36 percent increase from 2020. With an aging population, researchers say we must 'put the brakes' on low back pain cases before the burden becomes too great for our healthcare system.
Published Brain signatures for chronic pain identified in a small group of individuals (via sciencedaily.com) Original source
Researchers have recorded pain-related data from inside the brain of individuals with chronic pain disorders caused by stroke or amputation (phantom limb pain). A long sought-after goal has been to understand how pain is represented by brain activity and how to modulate that activity to relieve suffering from chronic pain. Data were collected over months while patients were at home, and they were analyzed using machine learning tools. Doing so, the researchers identified an area of the brain associated with chronic pain and objective biomarkers of chronic pain in individual patients.
Published 10 pesticides toxic to neurons involved in Parkinson's (via sciencedaily.com) Original source
Through a novel pairing of epidemiology and toxicity screening, researchers were able to identify 10 pesticides that were directly toxic to key neurons.
Published Researchers pinpoint brain cells that drive appetite in obesity (via sciencedaily.com) Original source
A group of brain cells discovered by researchers reveals a potential new approach to anti-obesity treatment.