Showing 20 articles starting at article 1
Published Treating newly-diagnosed Crohn's patients with advanced therapy leads to dramatic improvements in outcomes (via sciencedaily.com) Original source
A large-scale clinical trial of treatment strategies for Crohn's disease has shown that offering early advanced therapy to all patients straight after diagnosis can drastically improve outcomes, including by reducing the number of people requiring urgent abdominal surgery for treatment of their disease by ten-fold.
Published Researchers are using RNA in a new approach to fight HIV (via sciencedaily.com) Original source
A pharmacy associate professor has developed a novel nanomedicine loaded with genetic material called small interfering RNAs (siRNA) to fight human immunodeficiency virus (HIV) using gene therapy.
Published Double risk of dementia after mouth ulcer virus (via sciencedaily.com) Original source
People who have had the herpes virus at some point in their lives are twice as likely to develop dementia compared to those who have never been infected. A new study confirms previous research on whether herpes can be a possible risk factor for dementia.
Published Mood interventions may reduce inflammation in Crohn's and Colitis (via sciencedaily.com) Original source
New research reveals that interventions which improve mood can reduce levels of inflammation in people with inflammatory bowel disease by 18 per cent, compared to having no mood intervention.
Published Genetic variants underlying male bisexual behavior, risk-taking linked to more children, study shows (via sciencedaily.com) Original source
Because same-sex sexual behavior does not result in offspring, evolutionary biologists have long wondered how the genes associated with this behavior have persisted in the human genome, and whether they will remain in the future. A new study suggests that part of the explanation -- specifically for male bisexuals -- has to do with risk-taking behavior.
Published Researchers reveal prevalence of persistent symptoms in patients with microscopic colitis (via sciencedaily.com) Original source
A new study examines how multiple factors contribute to the miscommunication and understanding of the digestive disease, microscopic colitis.
Published Comprehensive guideline on using biomarkers for monitoring Crohn's disease (via sciencedaily.com) Original source
New AGA guideline outlines reliable blood and stool tests to monitor inflammation that can reduce how often patients need invasive endoscopy.
Published Early life exposure to broccoli sprouts protects against colitis in inflammatory bowel disease (via sciencedaily.com) Original source
High fiber diets, like those that include broccoli sprouts or other cruciferous vegetables, may reduce disease symptoms and improve quality of life in patients with inflammatory bowel disease (IBD).
Published Body changes up to eight years before inflammatory bowel disease diagnosis (via sciencedaily.com) Original source
Researchers have shown that changes can be detected in blood tests up to eight years before a diagnosis of Crohn's disease and up to three years before a diagnosis of ulcerative colitis.
Published Risk of serious infection even in low-active IBD (via sciencedaily.com) Original source
Inflammatory bowel disease (IBD) is an independent risk factor for serious infection, even at very low levels of gastrointestinal inflammation.
Published A promising target to fight inflammatory bowel diseases (via sciencedaily.com) Original source
Inflammatory bowel diseases (IBDs), such as Crohn's disease or ulcerative colitis, arise when there is a dysregulation of cell signalling pathways, leading to a chronic inflammatory response. The gut inflammatory response relies on a chain reaction involving several molecules, including RIPK2 -- known to be a good target for inhibitors treating IBDs. Researchers from the Cusack group at EMBL Grenoble have provided new insights into the interactions between RIPK2 and XIAP, another molecule involved in the inflammatory response, during the downstream chain reaction. These results, when taken together with previous structural biology studies on RIPK2, offer valuable information for the development of therapeutics to treat inflammatory bowel diseases.
Published Fungi used in food production could lead to new probiotics (via sciencedaily.com) Original source
According to a new study, 2 fungi used to produce food products have potential probiotic effects on gut inflammation.
Published Morning-after pill more effective when taken with an anti-inflammatory painkiller, researchers find (via sciencedaily.com) Original source
A research team recently published findings on adding an anti-inflammatory painkiller used for arthritis pain to an oral emergency contraceptive pill (also known as the morning-after pill) to increase the effectiveness of pregnancy prevention.
Published Inflammatory bowel disease linked to atopic dermatitis (via sciencedaily.com) Original source
Adults with atopic dermatitis (AD) have a 34 percent increased risk of developing new-onset inflammatory bowel disease (IBD) compared with individuals who do not have the skin condition, and children have a 44 percent increased risk, according to a new study.
Published Syphilis transmission networks and antimicrobial resistance in England uncovered using genomics (via sciencedaily.com) Original source
Scientists use genomics to uncover syphilis transmission patterns in England, in a pioneering new approach for STI surveillance.
Published Developing a less invasive test for inflammatory bowel disease (via sciencedaily.com) Original source
Millions of Americans have inflammatory bowel disease (IBD), which occurs in one of two forms: Crohn's disease or ulcerative colitis. Though the two have similar symptoms, they require different treatment strategies, and tests to distinguish between them are invasive. Researchers now show that chains of sugar molecules are tacked onto antibodies differently in patients with the diseases, which could someday lead to a simple blood-based diagnostic test.
Published New study shows effectiveness of mpox vaccine (via sciencedaily.com) Original source
A new international study has shown mpox (formerly known as monkeypox) infections to be less severe among those who are vaccinated or had a previous infection in 2022, underlining the importance and effectiveness of vaccination.
Published Neonatal stem cells from the heart could treat Crohn's disease (via sciencedaily.com) Original source
Research found that direct injection of neonatal mesenchymal stem cells, derived from heart tissue discarded during surgery, reduces intestinal inflammation and promotes wound healing in a mouse model of Crohn's disease-like ileitis, an illness marked by chronic intestinal inflammation and progressive tissue damage. The study offers a promising new and alternative treatment approach that avoids the pitfalls of current Crohn's disease medications, including diminishing effectiveness, severe side effects and increased risk of gastrointestinal dysfunction.
Published Nanomedicine for treating inflammatory bowel disease (via sciencedaily.com) Original source
Chronic inflammatory bowel disease (IBD), such as Crohn's disease and ulcerative colitis, is on the rise worldwide. The benefits of current medications are limited by problematic side effects. A research team has now introduced a new method of treatment. It is based on nanoparticles that mimic a special carbohydrate layer (glycocalyx) located on inflamed bowel cells, and which trigger anti-inflammatory effects in the diseased sites in the intestine.
Published Scientists link genes to diet in inflammatory bowel disease (via sciencedaily.com) Original source
A study of the genetic variation that makes mice more susceptible to bowel inflammation after a high-fat diet has identified candidate genes which may drive inflammatory bowel disease (IBD) in humans.