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Categories: Breastfeeding, Crohn's Disease

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Crohn's Disease
Published

New Inflammatory Bowel Disease testing protocol could speed up diagnosis      (via sciencedaily.com)     Original source 

Patients with suspected inflammatory bowel disease (IBD) could benefit from better testing protocols that would reduce the need and lengthy wait for potentially unnecessary colonoscopies, a new study has found.

Chronic Illness Crohn's Disease Today's Healthcare
Published

Hope for treating autoimmune diseases      (via sciencedaily.com)     Original source 

A routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of debilitating autoimmune diseases. The Systemic Inflammation Index (SII) uses information from routine laboratory data to measure inflammation in the body and examining this index in a new way could provide vital answers.

Crohn's Disease Today's Healthcare
Published

Gene analysis generates spatial map of intestinal cells and traces their trajectories during gut inflammation      (via sciencedaily.com)     Original source 

Cells within the intestines perform various roles including nutrient absorption, sensing, and maintaining homeostasis. Certain chronic disorders are distinctly characterized by gut inflammation, which disrupts intestinal cells and can lead to a remodeling of the gut and the introduction of new immune cells. To better understand the types of cells and their positioning within the intestines, researchers used a new technique known as MERFISH (multiplexed-error robust-fluorescence in situ hybridization) to analyze 940 genes in 1.35 million intestinal cells in a mouse model of colitis.

Breastfeeding Diet and Weight Loss Infant's Health
Published

Infant gut microbes have their own circadian rhythm, and diet has little impact on how the microbiome assembles      (via sciencedaily.com)     Original source 

Infant gut microbiomes oscillate with a circadian rhythm, even when they are cultivated outside of the body. Researchers report that the rhythm is detectable as early as 2 weeks after birth but becomes more pronounced with age. The finding comes from a randomized controlled trial that also showed that diet has less impact on the development and composition of the infant microbiome than previously thought.

Chronic Illness Crohn's Disease
Published

Implantable sensor could lead to timelier Crohn's treatment      (via sciencedaily.com)     Original source 

Scientists have developed the first wireless, implantable temperature sensor to detect inflammatory flareups in patients with Crohn's disease. The approach offers long-term, real-time monitoring and could enable clinicians to act earlier to prevent or limit the permanent damage caused by inflammatory episodes.

Crohn's Disease
Published

New understanding of the gut immune system may hold promise for Crohn's disease patients      (via sciencedaily.com)     Original source 

Scientists uncovered an overlooked mechanism in the gut immune system of patients suffering from severe cases of Crohn's disease. The discovery may help define how to treat patients with severe Crohn's disease.

Breastfeeding Infant's Health Nutrition Today's Healthcare
Published

Infant health suffered during baby formula shortage      (via sciencedaily.com)     Original source 

A survey by UC Davis researchers shows the U.S. baby formula shortage in 2022 led 81% of parents to switch brands or types, causing health effects for babies.

Breastfeeding Infant's Health
Published

Breastfeeding after COVID-19 booster can give babies antibodies      (via sciencedaily.com)     Original source 

A recently published study that shows lactating mothers who get the COVID-19 booster pass along the antibodies to their children via their breast milk -- and potentially protect babies too young to receive the vaccine.

Crohn's Disease Today's Healthcare
Published

Treating newly-diagnosed Crohn's patients with advanced therapy leads to dramatic improvements in outcomes      (via sciencedaily.com)     Original source 

A large-scale clinical trial of treatment strategies for Crohn's disease has shown that offering early advanced therapy to all patients straight after diagnosis can drastically improve outcomes, including by reducing the number of people requiring urgent abdominal surgery for treatment of their disease by ten-fold.

Chronic Illness Crohn's Disease Mental Health Research Today's Healthcare
Published

Mood interventions may reduce inflammation in Crohn's and Colitis      (via sciencedaily.com)     Original source 

New research reveals that interventions which improve mood can reduce levels of inflammation in people with inflammatory bowel disease by 18 per cent, compared to having no mood intervention.

Breastfeeding Infant's Health Today's Healthcare
Published

Study on extremely preterm infants provides important healthcare knowledge      (via sciencedaily.com)     Original source 

Infants born extremely prematurely need to get enrichment as an addition to breast milk. But does it make any difference whether the enrichment is made from breast milk or cow's milk when it comes to the risk of severe complications in children?

Chronic Illness Crohn's Disease
Published

Researchers reveal prevalence of persistent symptoms in patients with microscopic colitis      (via sciencedaily.com)     Original source 

A new study examines how multiple factors contribute to the miscommunication and understanding of the digestive disease, microscopic colitis.

Breastfeeding Child Development Children's Health Infant and Preschool Learning Infant's Health Parenting
Published

Breastfeeding alters infant gut in ways that boost brain development, may improve test scores      (via sciencedaily.com)     Original source 

Breastfeeding, even partially alongside formula feeding, changes the chemical makeup -- or metabolome -- of an infant's gut in ways that positively influence brain development and may boost test scores years later, suggests new research.  

Breastfeeding Child Development Children's Health Infant and Preschool Learning Infant's Health Parenting
Published

Mothers need more 'exclusive breastfeeding' support      (via sciencedaily.com)     Original source 

Exclusive breastfeeding for the first six months of life is proven to protect both mother and child health. According to the World Health Organization (WHO), between 2015 and 2021, 48% of mothers exclusively breastfed, meaning that their babies were not given any other food or liquids. However, this figure is based on data collected from surveys which report what a child was given in the previous 24 hours. A research team has found that this '24-hour recall' method overestimates exclusive breastfeeding by about six times compared to a 'since-birth recall' method.

Breastfeeding Child Development Dietary Supplements and Minerals Infant and Preschool Learning Infant's Health Nutrition Parenting Pregnancy and Childbirth Vitamin Women's Health - General
Published

How pre- and postnatal B-12 vitamins improve breast milk vitamin B-12 levels, which supports infant brain development      (via sciencedaily.com)     Original source 

According to a new study B-12 vitamins increase the presence of the micronutrient in mothers' breast milk, which is especially helpful in countries where it can be difficult to eat what is needed for the body to produce B-12 naturally.

Chronic Illness Crohn's Disease Today's Healthcare
Published

Comprehensive guideline on using biomarkers for monitoring Crohn's disease      (via sciencedaily.com)     Original source 

New AGA guideline outlines reliable blood and stool tests to monitor inflammation that can reduce how often patients need invasive endoscopy. 

Crohn's Disease Diet and Weight Loss Nutrition
Published

Early life exposure to broccoli sprouts protects against colitis in inflammatory bowel disease      (via sciencedaily.com)     Original source 

High fiber diets, like those that include broccoli sprouts or other cruciferous vegetables, may reduce disease symptoms and improve quality of life in patients with inflammatory bowel disease (IBD).

Chronic Illness Crohn's Disease
Published

Body changes up to eight years before inflammatory bowel disease diagnosis      (via sciencedaily.com)     Original source 

Researchers have shown that changes can be detected in blood tests up to eight years before a diagnosis of Crohn's disease and up to three years before a diagnosis of ulcerative colitis.

Chronic Illness Crohn's Disease Irritable Bowel Syndrome
Published

Risk of serious infection even in low-active IBD      (via sciencedaily.com)     Original source 

Inflammatory bowel disease (IBD) is an independent risk factor for serious infection, even at very low levels of gastrointestinal inflammation.

Crohn's Disease
Published

A promising target to fight inflammatory bowel diseases      (via sciencedaily.com)     Original source 

Inflammatory bowel diseases (IBDs), such as Crohn's disease or ulcerative colitis, arise when there is a dysregulation of cell signalling pathways, leading to a chronic inflammatory response. The gut inflammatory response relies on a chain reaction involving several molecules, including RIPK2 -- known to be a good target for inhibitors treating IBDs. Researchers from the Cusack group at EMBL Grenoble have provided new insights into the interactions between RIPK2 and XIAP, another molecule involved in the inflammatory response, during the downstream chain reaction. These results, when taken together with previous structural biology studies on RIPK2, offer valuable information for the development of therapeutics to treat inflammatory bowel diseases.