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Categories: Crohn's Disease, Hormone Disorders

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Crohn's Disease Today's Healthcare
Published

New Inflammatory Bowel Disease testing protocol could speed up diagnosis      (via sciencedaily.com)     Original source 

Patients with suspected inflammatory bowel disease (IBD) could benefit from better testing protocols that would reduce the need and lengthy wait for potentially unnecessary colonoscopies, a new study has found.

Chronic Illness Crohn's Disease Today's Healthcare
Published

Hope for treating autoimmune diseases      (via sciencedaily.com)     Original source 

A routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of debilitating autoimmune diseases. The Systemic Inflammation Index (SII) uses information from routine laboratory data to measure inflammation in the body and examining this index in a new way could provide vital answers.

Crohn's Disease Today's Healthcare
Published

Gene analysis generates spatial map of intestinal cells and traces their trajectories during gut inflammation      (via sciencedaily.com)     Original source 

Cells within the intestines perform various roles including nutrient absorption, sensing, and maintaining homeostasis. Certain chronic disorders are distinctly characterized by gut inflammation, which disrupts intestinal cells and can lead to a remodeling of the gut and the introduction of new immune cells. To better understand the types of cells and their positioning within the intestines, researchers used a new technique known as MERFISH (multiplexed-error robust-fluorescence in situ hybridization) to analyze 940 genes in 1.35 million intestinal cells in a mouse model of colitis.

Chronic Illness Crohn's Disease
Published

Implantable sensor could lead to timelier Crohn's treatment      (via sciencedaily.com)     Original source 

Scientists have developed the first wireless, implantable temperature sensor to detect inflammatory flareups in patients with Crohn's disease. The approach offers long-term, real-time monitoring and could enable clinicians to act earlier to prevent or limit the permanent damage caused by inflammatory episodes.

Hormone Disorders
Published

Steroid drugs used for HRT can combat E. coli and MRSA      (via sciencedaily.com)     Original source 

Researchers have combined computational and microbiology laboratory approaches to identify existing drugs that can be repurposed to combat antibiotic-resistant bacterial infections. This research has revealed that a class of steroid drugs currently used in hormone replacement therapy (HRT) can also stop the growth of antibiotic-resistant E. coli and effectively kill MRSA.

Crohn's Disease
Published

New understanding of the gut immune system may hold promise for Crohn's disease patients      (via sciencedaily.com)     Original source 

Scientists uncovered an overlooked mechanism in the gut immune system of patients suffering from severe cases of Crohn's disease. The discovery may help define how to treat patients with severe Crohn's disease.

Hormone Disorders
Published

Latest science shows endocrine disrupting chemicals in plastics, pesticides, and other sources pose health threats globally      (via sciencedaily.com)     Original source 

A report from the world's leading scientific and medical experts on hormone-related health conditions raises new concerns about the profound threats to human health from endocrine disrupting chemicals (EDCs) that are ubiquitous in our surroundings and everyday lives. Everyday exposures to EDCs in the environment may be linked to increasing rates of infertility, diabetes, immune deficiencies, and other serious conditions; Highly Hazardous Pesticides pose ongoing threats.

Crohn's Disease Today's Healthcare
Published

Treating newly-diagnosed Crohn's patients with advanced therapy leads to dramatic improvements in outcomes      (via sciencedaily.com)     Original source 

A large-scale clinical trial of treatment strategies for Crohn's disease has shown that offering early advanced therapy to all patients straight after diagnosis can drastically improve outcomes, including by reducing the number of people requiring urgent abdominal surgery for treatment of their disease by ten-fold.

Chronic Illness Crohn's Disease Mental Health Research Today's Healthcare
Published

Mood interventions may reduce inflammation in Crohn's and Colitis      (via sciencedaily.com)     Original source 

New research reveals that interventions which improve mood can reduce levels of inflammation in people with inflammatory bowel disease by 18 per cent, compared to having no mood intervention.

Fertility Hormone Disorders Psychology Research
Published

Brain cell discovery sparks hope for fertility treatments      (via sciencedaily.com)     Original source 

Researchers have demonstrated how a specific type of neuron in the brain affects the release of hormones that control ovarian function in females. These findings could help researchers understand and treat reproductive disorders in both animals and humans.

Chronic Illness Crohn's Disease
Published

Researchers reveal prevalence of persistent symptoms in patients with microscopic colitis      (via sciencedaily.com)     Original source 

A new study examines how multiple factors contribute to the miscommunication and understanding of the digestive disease, microscopic colitis.

Diabetes Hormone Disorders
Published

Stimulating nerves connected to the pancreas regenerates insulin-producing cells, mouse study shows      (via sciencedaily.com)     Original source 

Decreasing pancreatic beta cell numbers -- the only cells that produce insulin -- is a leading cause of diabetes. In a promising development, a research group has revealed that stimulating autonomic vagal nerves connected to the pancreas can improve the function and also increase the number of pancreatic beta cells in mice.

Hormone Disorders
Published

Why does puberty trigger us to stop growing?      (via sciencedaily.com)     Original source 

Research on fruit flies has implications for this poorly understood process in humans.

Chronic Illness Hormone Disorders Thyroid Disease
Published

Anti-rheumatic drugs could prevent thyroid disease      (via sciencedaily.com)     Original source 

Anti-rheumatic drugs used for rheumatoid arthritis might prevent the development of autoimmune thyroid disease, according to a new observational study.

Chronic Illness Crohn's Disease Today's Healthcare
Published

Comprehensive guideline on using biomarkers for monitoring Crohn's disease      (via sciencedaily.com)     Original source 

New AGA guideline outlines reliable blood and stool tests to monitor inflammation that can reduce how often patients need invasive endoscopy. 

Hormone Disorders
Published

Excessive fluid consumption: Habit or hormonal disorder?      (via sciencedaily.com)     Original source 

People who drink more than three liters of fluid a day may be suffering from a rare hormone deficiency. For many, however, it is just a harmless habit. Failing to differentiate the two correctly can be fatal, so researchers have been investigating what kind of test delivers a reliable diagnosis.

Crohn's Disease Diet and Weight Loss Nutrition
Published

Early life exposure to broccoli sprouts protects against colitis in inflammatory bowel disease      (via sciencedaily.com)     Original source 

High fiber diets, like those that include broccoli sprouts or other cruciferous vegetables, may reduce disease symptoms and improve quality of life in patients with inflammatory bowel disease (IBD).

Chronic Illness Crohn's Disease
Published

Body changes up to eight years before inflammatory bowel disease diagnosis      (via sciencedaily.com)     Original source 

Researchers have shown that changes can be detected in blood tests up to eight years before a diagnosis of Crohn's disease and up to three years before a diagnosis of ulcerative colitis.

Chronic Illness Crohn's Disease Irritable Bowel Syndrome
Published

Risk of serious infection even in low-active IBD      (via sciencedaily.com)     Original source 

Inflammatory bowel disease (IBD) is an independent risk factor for serious infection, even at very low levels of gastrointestinal inflammation.

Crohn's Disease
Published

A promising target to fight inflammatory bowel diseases      (via sciencedaily.com)     Original source 

Inflammatory bowel diseases (IBDs), such as Crohn's disease or ulcerative colitis, arise when there is a dysregulation of cell signalling pathways, leading to a chronic inflammatory response. The gut inflammatory response relies on a chain reaction involving several molecules, including RIPK2 -- known to be a good target for inhibitors treating IBDs. Researchers from the Cusack group at EMBL Grenoble have provided new insights into the interactions between RIPK2 and XIAP, another molecule involved in the inflammatory response, during the downstream chain reaction. These results, when taken together with previous structural biology studies on RIPK2, offer valuable information for the development of therapeutics to treat inflammatory bowel diseases.