Showing 20 articles starting at article 1
Categories: Birth Defects, Mental Health Research
Published Neural signature for borderline personality disorder identified
(via sciencedaily.com) Original source A new study of a brain region called the rostro-medial prefrontal could potentially advance diagnosis and therapies for Borderline Personality Disorder (BPD).
Published Human embryo-like models created from stem cells to understand earliest stages of human development
(via sciencedaily.com) Original source Scientists have created a stem cell-derived model of the human embryo in the lab by reprogramming human stem cells. The breakthrough could help research into genetic disorders and in understanding why and how pregnancies fail.
Published Poor sense of smell linked to increased risk of depression in older adults
(via sciencedaily.com) Original source In a study that followed more than 2,000 community-dwelling older adults over eight years, researchers say they have significant new evidence of a link between decreased sense of smell and risk of developing late-life depression.
Published A subtype of depression identified
(via sciencedaily.com) Original source Using surveys, cognitive tests and brain imaging, researchers have identified a type of depression that affects about a quarter of patients. The goal is to diagnose and treat the condition more precisely.
Published Chronic stress-related neurons identified
(via sciencedaily.com) Original source Researchers have identified a group of nerve cells in the mouse brain that are involved in creating negative emotional states and chronic stress. The neurons, which have been mapped with a combination of advanced techniques, also have receptors for estrogen, which could explain why women as a group are more sensitive to stress than men.
Published What role does alternative splicing play in neurodegenerative disease?
(via sciencedaily.com) Original source Scientists have written a review to discuss emerging research and evidence of the roles of alternative splicing defects in major neurodegenerative diseases. They also summarize the latest advances in RNA-based therapeutic strategies to target these disorders.
Published Serotonin booster leads to increased functional brain connectivity
(via sciencedaily.com) Original source Cognitive deficits accompany mood disorders and other psychiatric conditions, often with debilitating effects. Limited treatments currently exist, but studies in animals and humans have pointed to drugs such as the laxative prucalopride that activate serotonin receptors as a potential therapeutic for the symptoms. It has remained unclear, however, how the medication affects resting brain activity. Now, a new study examines the drug's effects in healthy human adults.
Published New study links contraceptive pills and depression
(via sciencedaily.com) Original source Women who used combined contraceptive pills were at greater risk of developing depression than women who did not, according to a new study. Contraceptive pills increased women's risk by 73 per cent during the first two years of use.
Published New research identifies cells linking chronic psychological stress to inflammatory bowel disease
(via sciencedaily.com) Original source For the first time, cells involved with the communication between stress responses in the brain and inflammation in the gastrointestinal (GI) tract have been identified in animal models. Glial cells, which support neurons, communicate stress signals from the central nervous system (CNS) to the semi-autonomous nervous system within the gastrointestinal (GI) tract, called the enteric nervous system (ENS). These psychological stress signals can cause inflammation and exacerbate symptoms of inflammatory bowel disease (IBD).
Published Poorly insulated nerve cells promote Alzheimer's disease in old age
(via sciencedaily.com) Original source Researchers have shown that defective myelin actively promotes disease-related changes in Alzheimer's disease.
Published Open-analysis platform for pediatric brain tumors provides robust data resource for childhood cancer research
(via sciencedaily.com) Original source Researchers have partnered to create a first-of-its-kind open-source, reproducible analysis platform for pediatric brain tumors. With the help of thousands of genomically sequenced samples, researchers have used this platform to identify initial findings about genetic variants associated with poorer outcomes that could help guide future diagnostic and therapeutic advances.
Published Scientists unveil RNA-guided mechanisms driving cell fate
(via sciencedaily.com) Original source The early stages of embryonic development contain many of life's mysteries. Unlocking these mysteries can help us better understand early development and birth defects, and help develop new regenerative medicine treatments. Researchers have now characterized a critical time in mammalian embryonic development using powerful and innovative imaging techniques.
Published Obesity increases risk of mental disorders throughout life
(via sciencedaily.com) Original source Being obese significantly increases the chances of also developing mental disorders. This applies to all age groups, with women at higher risk than men for most diseases.
Published A student's poor eating habits can lead to a lifetime of illness
(via sciencedaily.com) Original source A researcher is cautioning that a person's poor eating habits established during post-secondary studies can contribute to future health issues including obesity, respiratory illnesses and depression.
Published Researchers treat depression by reversing brain signals traveling the wrong way
(via sciencedaily.com) Original source A new study has revealed how magnetic stimulation treats severe depression: by correcting the abnormal flow of brain signals.
Published AI voice coach shows promise in depression, anxiety treatment
(via sciencedaily.com) Original source A study found changes in patients' brain activity along with improved depression and anxiety symptoms after using Lumen.
Published Understanding the speed of brain communication
(via sciencedaily.com) Original source Called the human connectome, this structural system of neural pathways develops as people age. A new study shows transmission speed among brain regions increases into early adulthood. Learning more about neuron transmission may improve the understanding of psychological disorders.
Published Anti-depressant agent KNT-127 reduces stress as well as depression
(via sciencedaily.com) Original source Depression is a condition affecting millions across the globe. However, efficient drugs with minimal adverse effects are scarce. Now, researchers have reported how KNT-127, a delta opioid receptor agonist, quickly and efficiently reduces classic parameters of depression in a mouse model. This anti-depressant agent exhibits the dual nature of being a stress reliever and an anti-depressant and could broaden the potential of existing treatments.
Published A special omega-3 fatty acid lipid will change how we look at the developing and aging brain
(via sciencedaily.com) Original source Scientists have found a lipid transporter crucial to regulating the cells that make myelin, the nerve-protecting sheath.
Published Gene responsible for severe facial defects identified
(via sciencedaily.com) Original source Goldenhar syndrome is a rare congenital disease, affecting early fetal development. This syndrome includes malformations of varying severity, affecting different parts of the face. Its causes and modes of transmission are still poorly understood. An international collaboration has discovered that pathogenic variants of the FOXI3 gene -- responsible for the development of the ear -- cause one form of this developmental disorder. The scientists were also able to identify the modes of transmission of the disease when this particular gene is involved.