Showing 20 articles starting at article 1
Categories: Chronic Illness, Mental Health Research
Published Neural signature for borderline personality disorder identified



A new study of a brain region called the rostro-medial prefrontal could potentially advance diagnosis and therapies for Borderline Personality Disorder (BPD).
Published Poor sense of smell linked to increased risk of depression in older adults



In a study that followed more than 2,000 community-dwelling older adults over eight years, researchers say they have significant new evidence of a link between decreased sense of smell and risk of developing late-life depression.
Published A subtype of depression identified



Using surveys, cognitive tests and brain imaging, researchers have identified a type of depression that affects about a quarter of patients. The goal is to diagnose and treat the condition more precisely.
Published Study sets new standard for graft-versus-host disease prevention after stem cell transplant



Clinicians have a new standard for graft-versus-host disease (GVHD) prevention after allogeneic hematopoietic stem cell transplantation, according to results from a phase III study. The new standard is more effective at preventing GVHD and came with less side effects, compared with the current gold standard.
Published Chronic stress-related neurons identified



Researchers have identified a group of nerve cells in the mouse brain that are involved in creating negative emotional states and chronic stress. The neurons, which have been mapped with a combination of advanced techniques, also have receptors for estrogen, which could explain why women as a group are more sensitive to stress than men.
Published Pain not perceived in the same way in people with Alzheimer's Disease



New research has found that in a mouse model mimicking Alzheimer's Disease (AD) pain signals are not processed in the same way as in healthy mice.
Published Omega-3 fatty acids linked to slower decline in ALS



People with amyotrophic lateral sclerosis (ALS) who eat more foods high in certain omega-3 fatty acids like flaxseed oil, walnuts, canola oil and pumpkin seeds may have a slower physical decline from the disease and may have a slightly extended survival. Researchers also found an omega-6 fatty acid may be beneficial. The study does not prove that these omega fatty acids slow decline of ALS or extend survival; it only shows an association.
Published Blood pressure drug could prevent post-traumatic headaches



A study has shown that prazosin, a drug used to treat high blood pressure, can prevent post-traumatic headaches.
Published New findings show mitochondrial DNA fragments in blood as important biomarkers for aging and inflammation



In an eight-year study of more than 600 community-dwelling older adults, researchers say they have further linked levels of cell-free DNA (DNA fragments resulting from cell death) circulating in the blood to chronic inflammation and frailty. The study is novel and expands on previous work, the investigators say, because it focused on mitochondrial DNA rather than solely genomic DNA, as previously reported.
Published What role does alternative splicing play in neurodegenerative disease?



Scientists have written a review to discuss emerging research and evidence of the roles of alternative splicing defects in major neurodegenerative diseases. They also summarize the latest advances in RNA-based therapeutic strategies to target these disorders.
Published Serotonin booster leads to increased functional brain connectivity



Cognitive deficits accompany mood disorders and other psychiatric conditions, often with debilitating effects. Limited treatments currently exist, but studies in animals and humans have pointed to drugs such as the laxative prucalopride that activate serotonin receptors as a potential therapeutic for the symptoms. It has remained unclear, however, how the medication affects resting brain activity. Now, a new study examines the drug's effects in healthy human adults.
Published Researchers uncover why light-to-moderate drinking is tied to better heart health



A new study offers an explanation for why light-to-moderate alcohol consumption may be associated with lower risk of heart disease. For the first time, researchers found that alcohol, in light to moderate quantities, was associated with long-term reductions in stress signaling in the brain.
Published New study links contraceptive pills and depression



Women who used combined contraceptive pills were at greater risk of developing depression than women who did not, according to a new study. Contraceptive pills increased women's risk by 73 per cent during the first two years of use.
Published New research identifies cells linking chronic psychological stress to inflammatory bowel disease



For the first time, cells involved with the communication between stress responses in the brain and inflammation in the gastrointestinal (GI) tract have been identified in animal models. Glial cells, which support neurons, communicate stress signals from the central nervous system (CNS) to the semi-autonomous nervous system within the gastrointestinal (GI) tract, called the enteric nervous system (ENS). These psychological stress signals can cause inflammation and exacerbate symptoms of inflammatory bowel disease (IBD).
Published Sea cucumbers: The marine delicacy that can deter diabetes



They're a marine delicacy loved across Asia, but the humble sea cucumber is also proving to be a key ingredient in preventing diabetes, according to new research.
Published Poorly insulated nerve cells promote Alzheimer's disease in old age



Researchers have shown that defective myelin actively promotes disease-related changes in Alzheimer's disease.
Published Parkinson's disease drug ropinirole safely slowed the progression of ALS for over 6 months in a clinical trial



Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a fatal motor neuron disease that causes people to gradually lose control of their muscles. There is no cure, and current treatments focus on reducing symptoms and providing supportive care. Researchers now show in an early clinical trial that the Parkinson's disease drug ropinirole is safe to use in ALS patients and delayed disease progression by 27.9 weeks on average.
Published Engineers report low-cost human biomarker sensor designs



Researchers have developed a low-cost, RNA-based technology to detect and measure biomarkers, which can help decode the body's physiology. The presence of protein biomarkers can indicate chronic or acute conditions, from arthritis to cancer to bacterial infections, for which conventional tests can cost anywhere from $100 to upwards of $1,000. The new technology can perform the same measurement for about a dollar.
Published Obesity increases risk of mental disorders throughout life



Being obese significantly increases the chances of also developing mental disorders. This applies to all age groups, with women at higher risk than men for most diseases.
Published A student's poor eating habits can lead to a lifetime of illness



A researcher is cautioning that a person's poor eating habits established during post-secondary studies can contribute to future health issues including obesity, respiratory illnesses and depression.