Showing 20 articles starting at article 1
Published Scientists take next big step in understanding genetics of schizophrenia (via sciencedaily.com) Original source
Scientists are figuring out which of the 5,000 variants associated with schizophrenia have an actual causal effect in the development of the condition that affects millions of people worldwide.
Published Schizophrenia genetic risk factor impairs mitochondrial function (via sciencedaily.com) Original source
Researcher discovers possible link of mitochondrial function to the development of schizophrenia.
Published New neuroimaging approach could improve diagnosis of schizophrenia (via sciencedaily.com) Original source
New research has identified age-related changes in brain patterns associated with the risk for developing schizophrenia. The discovery could help clinicians identify the risk for developing mental illness earlier and improve treatment options.
Published Schizophrenia is associated with somatic mutations occurring in utero (via sciencedaily.com) Original source
As a psychiatric disorder with onset in adulthood, schizophrenia is thought to be triggered by some combination of environmental factors and genetics, although the exact cause is still not fully understood. Researchers have now found a correlation between schizophrenia and somatic copy-number variants, a type of mutation that occurs early in development but after genetic material is inherited. This study is one of the first to rigorously describe the relationship between somatic -- not inherited -- genetic mutations and schizophrenia risk.
Published Research challenges current thinking on the genetic causes of very early menopause (via sciencedaily.com) Original source
The genetic causes of very early menopause will have to be reconsidered after researchers found that nearly all women who carried variations thought to cause the condition in fact had their menopause at an older age.
Published Helping 'good' gut bacteria and clearing out the 'bad' -- all in one treatment (via sciencedaily.com) Original source
Probiotics can help maintain a healthy gut microbiome or restore populations of 'good bacteria' after a heavy course of antibiotics. But now, they could also be used as an effective treatment strategy for certain intestinal diseases, such as Crohn's disease. Researchers have developed a microgel delivery system for probiotics that keeps 'good' bacteria safe while actively clearing out 'bad' ones. In mice, the system treated intestinal inflammation without side effects.
Published A 'pinch' of mineral salts helps the noncaloric sweeteners go down (via sciencedaily.com) Original source
Perfect noncaloric replacements for sugar and high fructose corn syrup just don't exist yet. For example, some alternatives have a lingering sweet aftertaste and lack a sugar-like mouthfeel, leaving some consumers unsatisfied. Now, researchers propose adding blends of nutritionally important mineral salts to make noncaloric sweeteners seem more like the real thing. Taste-testers indicated that these blends gave zero- and low-calorie drinks a better flavor.
Published New study links contraceptive pills and depression (via sciencedaily.com) Original source
Women who used combined contraceptive pills were at greater risk of developing depression than women who did not, according to a new study. Contraceptive pills increased women's risk by 73 per cent during the first two years of use.
Published How does dopamine regulate both learning and motivation? (via sciencedaily.com) Original source
A new study brings together two schools of thought on the function of the neurotransmitter dopamine: one saying that dopamine provides a learning signal, the other saying that dopamine drives motivation.
Published Further link identified between autoimmunity and schizophrenia (via sciencedaily.com) Original source
Links have been reported between schizophrenia and proteins produced by the immune system that can act against one's own body, known as autoantibodies. Researchers have now identified autoantibodies that target a 'synaptic adhesion protein' in a subset of patients with schizophrenia. When injected into mice, the autoantibodies caused many schizophrenia-related changes.
Published Vitamin D alters developing neurons in the brain's dopamine circuit (via sciencedaily.com) Original source
Neuroscientists have shown how vitamin D deficiency affects developing neurons in the brain's dopamine circuit, which may lead to the dopamine dysfunction seen in adults with schizophrenia.
Published How breast cancer arises (via sciencedaily.com) Original source
Researchers trace the origin of certain breast cancers to genomic reshuffling -- rearrangement of chromosomes -- that activates cancer genes and ignites disease. The finding offers a long-missing explanation for many cases of the disease that remain unexplained by the classical model of breast cancer development. The study shows the sex hormone estrogen -- thus far thought to be only a fuel for breast cancer growth -- can directly cause tumor-driving genomic rearrangements.
Published A special omega-3 fatty acid lipid will change how we look at the developing and aging brain (via sciencedaily.com) Original source
Scientists have found a lipid transporter crucial to regulating the cells that make myelin, the nerve-protecting sheath.
Published Gamma delta T cells can fight aggressive breast cancer (via sciencedaily.com) Original source
Researchers discover a mechanism by which cancer cells escape the immune system.
Published Osteoporosis treatments may benefit from discovery of key driver of low bone density (via sciencedaily.com) Original source
Scientists have pinpointed a key driver of low bone density, a discovery that may lead to improved treatments with fewer side effects for women with osteoporosis. The findings reveal that loss of an epigenetic modulator, KDM5C, preserves bone mass in mice. KDM5C works by altering epigenetic 'marks,' which are akin to 'on' and 'off' switches that ensure the instructions written in DNA are used at the right time and in the right place.
Published Early menopause, later start to hormone therapy may increase risk of Alzheimer's disease (via sciencedaily.com) Original source
Women are more likely than men to develop Alzheimer's disease (AD), with women making up two-thirds of the population living with AD. A new study sheds light on the relationship between the risk of Alzheimer's disease and age of menopause and use of hormone therapy (HT).
Published Is bone health linked to brain health? (via sciencedaily.com) Original source
People who have low bone density may have an increased risk of developing dementia compared to people who have higher bone density. The study does not prove that low bone density causes dementia. It only shows an association.
Published Study finds similar association of progestogen-only and combined hormonal contraceptives with breast cancer risk (via sciencedaily.com) Original source
There is a relative increase of 20% to 30% in breast cancer risk associated with both combined and progesterone-only contraceptives, whatever the mode of delivery, though with five years of use, the 15-year absolute excess incidence is at most 265 cases per 100,000 users, according to a new study.
Published Disproportionate percentage of females with unexplained infertility have gene variants known to cause heart problems, cancer (via sciencedaily.com) Original source
About 17% of women with unexplained infertility also have gene variants known to cause disease, from common conditions like heart disease to rare problems like ALS, researchers report.
Published Humans bite back by deactivating mosquito sperm (via sciencedaily.com) Original source
New research makes it likely that proteins responsible for activating mosquito sperm can be shut down, preventing them from swimming to or fertilizing eggs.