Showing 20 articles starting at article 1
Published How pre- and postnatal B-12 vitamins improve breast milk vitamin B-12 levels, which supports infant brain development (via sciencedaily.com) Original source
According to a new study B-12 vitamins increase the presence of the micronutrient in mothers' breast milk, which is especially helpful in countries where it can be difficult to eat what is needed for the body to produce B-12 naturally.
Published Novel molecular mechanisms in the early development of diabetes mellitus (via sciencedaily.com) Original source
Researchers conducted a gene expression analysis at the single-cell level on pancreatic islets from prediabetic and diabetic mouse models. Analysis results revealed upregulation of Anxa10 expression in pancreatic beta cells during the early phases of diabetes, attributed to elevated blood glucose levels. This elevated Anxa10 expression was found to influence intracellular calcium homeostasis, leading to a reduction in insulin secretory capacity.
Published Urban environmental exposures drive increased breast cancer incidence (via sciencedaily.com) Original source
An analysis of breast cancer showed that the state’s urban counties had higher overall incidences of disease than rural counties, especially at early stages upon diagnosis.
Published New compound outperforms pain drug by indirectly targeting calcium channels (via sciencedaily.com) Original source
A compound -- one of 27 million screened in a library of potential new drugs -- reversed four types of chronic pain in animal studies, according to new research. The small molecule, which binds to an inner region of a calcium channel to indirectly regulate it, outperformed gabapentin without troublesome side effects, providing a promising candidate for treating pain.
Published Side-effect avoiding treatment shows early promise against breast cancer in mice (via sciencedaily.com) Original source
New experimental evidence suggests that substances known as narrow-spectrum Wnt signaling inhibitors -- which could have fewer side effects than other related substances -- are capable of suppressing the growth of breast cancer tumors in mice.
Published Blood clotting risk quickly drops after stopping hormonal contraceptives (via sciencedaily.com) Original source
Using birth control pills and other hormone-based contraceptives is known to elevate the risk of blood clots, but a new study suggests that this risk largely goes away within two to four weeks after one stops using these contraceptives. The findings can help patients and doctors weigh the benefits and risks of hormonal contraceptives and guide when to stop using them ahead of events that could further increase the risk of dangerous clots, such as major surgery, prolonged periods of immobility, or when tapering anticoagulant medications after a blood clot.
Published Visualizing fungal infections deep in living host tissue reveals proline metabolism facilitates virulence (via sciencedaily.com) Original source
Scientists have published the first successful application of 2-photon intravital microscopy (IVM) to image the dynamics of fungal infections in the kidney of a living host. The study reveals that the opportunistic human fungal pathogen Candida albicans requires the ability to metabolize proline, an amino acid obtained from the host, to mount virulent infections.
Published Higher risk of breast cancer in women with false positive mammography result (via sciencedaily.com) Original source
Women who receive a false positive mammography result are more likely to develop breast cancer over the subsequent 20 years, report researchers. The risk is highest for women aged between 60 and 75 and who have low breast density.
Published COVID vaccination in female, male partners does not increase risk of miscarriage, study finds (via sciencedaily.com) Original source
A new study provides deeper insight into the safety of COVID-19 vaccines for people planning to become pregnant. The study found no increased risk of early or late miscarriage as a result of male or female partners getting a COVID-19 vaccine prior to conceiving.
Published Cutting-edge imaging sheds new light on cells that break down bone (via sciencedaily.com) Original source
Imaging technology shows that bone-resorbing osteoclasts gather in distinct pockets, leading to new insights for osteoporosis and cancer treatment.
Published Researchers uncover mechanism that links NAD+ to fertility problems (via sciencedaily.com) Original source
A woman's fertility normally decreases by her late 30s with reproductive function eventually ceasing at menopause. It is known that a small molecule called nicotinamide adenine dinucleotide (NAD+) plays a critical role in this decline, and scientists have revealed how this happens and have identified potential new approaches to enhance reproductive longevity.
Published Fungal infection in the brain produces changes like those seen in Alzheimer's disease (via sciencedaily.com) Original source
Researchers have discovered how the fungus Candida albicans enters the brain, activates two separate mechanisms in brain cells that promote its clearance, and, important for the understanding of Alzheimer's disease development, generates amyloid beta (Ab)-like peptides, toxic protein fragments from the amyloid precursor protein that are considered to be at the center of the development of Alzheimer's disease.
Published Brain is 'rewired' during pregnancy to prepare for motherhood (via sciencedaily.com) Original source
Researchers have shown that pregnancy hormones ‘rewire’ the brain to prepare mice for motherhood. The findings show that both estrogen and progesterone act on a small population of neurons in the brain to switch on parental behavior even before offspring arrive. These adaptations resulted in stronger and more selective responses to pups.
Published Women living in more walkable neighborhoods have lower rates of obesity-related cancers (via sciencedaily.com) Original source
Residing in a more walkable neighborhood protects against the risk of overall obesity-related cancers in women, specifically postmenopausal breast cancer, but also ovarian cancer, endometrial cancer, and multiple myeloma, according to a new study. Obesity has been linked to increased risk for 13 types of cancer in women, and physical activity, independent of body size, lowers risk for some of these cancers. Until now long-term studies of neighborhood walkability and risk for obesity-related cancer were limited.
Published Is a longer reproductive lifespan good for your brain? (via sciencedaily.com) Original source
People with a higher cumulative estrogen exposure throughout their life may have a lower risk of cerebral small vessel disease, according to a new study.
Published Wearable patch wirelessly monitors estrogen in sweat (via sciencedaily.com) Original source
A new sensor may make it easier for women to monitor their estradiol, which plays a role in health and fertility.
Published Study finds significant chemical exposures in women with cancer (via sciencedaily.com) Original source
Exposure to endocrine-disrupting chemicals like PFAS and phenols are implicated in hormone-mediated cancers of the breast, ovaries, skin and uterus. To learn more about the environmental exposures experienced by women who developed these cancers, researchers analyzed data from NHANES and found that women who reported having cancer had significantly higher levels of these chemicals in their bodies.
Published New device rapidly controls postpartum hemorrhage (via sciencedaily.com) Original source
A study led by obstetricians has shown that a new device can rapidly control postpartum hemorrhage, a major cause of severe maternal morbidity and death, in a wide range of patients.
Published Natural compound found in plants inhibits deadly fungi (via sciencedaily.com) Original source
A new study finds that a natural compound found in many plants inhibits the growth of drug-resistant Candida fungi -- including its most virulent species, Candida auris, an emerging global health threat.
Published New method offers hope of fewer fractures (via sciencedaily.com) Original source
Thousands of people could be spared from a hip fracture each year if a new method to identify the risk of osteoporotic fractures were to be introduced in healthcare. This is the view of the researchers who are behind a new 3D-simulation method.