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Published Atopic dermatitis: Viruses discovered as new therapy option (via sciencedaily.com)
Up to 15 percent of children and five percent of adults are affected by the chronic inflammatory skin disease atopic dermatitis. Despite advanced therapy measures, the severe itching and eczema, especially on the elbows or knees, cause great distress to the patients. Medical researchers have now discovered a new approach: bacteriophages, which colonize the skin as viral components of the microbiome and can drive the development of innovative atopic dermatitis therapies.
Published Skin behind the ears and between the toes can host a collection of unhealthy microbes (via sciencedaily.com)
Scrubbing behind the ears and between the toes may help keep the skin in those regions healthy, new research suggests. The microbiome, or the collection of microbes living on and in the human body, are known to play a role in human health and the skin is no different. A new study has shown that the composition of the skin microbiome varies across dry, moist and oily regions of the skin.
Published Walking more than five flights of stairs a day can cut risk of heart disease by 20 percent, study says (via sciencedaily.com)
A new study has found that walking up more than five flights of stairs a day could reduce risk of cardiovascular disease by 20 percent.
Published Study pinpoints the length of incidental activity linked to health benefits (via sciencedaily.com)
A new wearables study tracking over 25,000 people provides the best evidence yet that short bouts of incidental activity, the kind we do as part of daily living, could reduce risk of heart attack, stroke and even premature death -- but the length of activity and intensity matters.
Published Increased risk of depression and anxiety when in higher education, study finds (via sciencedaily.com) Original source
Young people who are in higher education in England face a small increased risk of depression and anxiety, compared to their peers who are not attending higher education, finds a new study.
Published Genes fuelling antibiotic resistance in Yemen cholera outbreak uncovered (via sciencedaily.com)
Scientists have identified the source of antibiotic resistance that emerged within bacteria driving the ongoing Yemen cholera epidemic.
Published Malaria: Treatment of Plasmodium falciparum malaria patients under threat in the Horn of Africa (via sciencedaily.com)
Diagnosis of Plasmodium falciparum malaria using rapid diagnostic tests and treatment with artemisinin derivatives, the main component of the malaria treatments recommended by the World Health Organization (WHO), are under threat in the Horn of Africa. Scientists have detected the emergence and spread in Eritrea of parasites with both artemisinin resistance and genome modifications that prevent their detection with rapid diagnostic tests, thereby jeopardizing malaria control and elimination campaigns in the region and potentially elsewhere in Africa.
Published Novel tau PET tracer exhibits high sensitivity and specificity, allowing for earlier identification of Alzheimer's disease (via sciencedaily.com)
A new tau PET radiotracer, 18F-SNFT-1, has been found to be more effective than existing tau PET radiotracers in identifying Alzheimer’s disease in its earliest stages, according to research. In a head-to-head comparison, 18F-SNFT-1 possessed preferable brain pharmacokinetics and demonstrated higher affinity and selectivity for Alzheimer’s tau lesions compared to clinically used second-generation tau PET tracers.
Published Diabetes may accelerate blood cancer growth, yet survival outcomes differ by race (via sciencedaily.com)
Patients with multiple myeloma, a blood cancer of plasma cells in the bone marrow, who also have diabetes have a reduced overall survival when compared to those without diabetes. In a subgroup analysis, this difference in survival due to diabetes was seen in White patients but not in Black patients, according to a new study.
Published SARS-CoV-2-associated sepsis was more common, deadly than previously thought, study finds (via sciencedaily.com)
New research suggests that the virus responsible for COVID-19 was a more common and deadly cause of sepsis during the initial period of the pandemic than previously assumed.
Published Is a longer reproductive lifespan good for your brain? (via sciencedaily.com) Original source
People with a higher cumulative estrogen exposure throughout their life may have a lower risk of cerebral small vessel disease, according to a new study.
Published Risk of premature birth from smoking while pregnant more than double previous estimates (via sciencedaily.com)
Researchers have found that women who smoke during pregnancy are 2.6 times more likely to give birth prematurely compared to non-smokers -- more than double the previous estimate. The study also found that smoking meant that the baby was four times more likely to be small for its gestational age, putting it at risk of potentially serious complications including breathing difficulties and infections.
Published Job loss is linked to increased risk of miscarriage and stillbirth (via sciencedaily.com)
Researchers have found a link between a pregnant woman or her partner losing their job and an increased risk of miscarriage or stillbirth. The study found a doubling in the chances of a pregnancy miscarrying or resulting in a stillbirth following a job loss.
Published Fish reveal cause of altered human facial development (via sciencedaily.com)
Some substances in medicines, household items and the environment are known to affect prenatal child development. Researchers tested the effects of five drugs (including caffeine and the blood thinner warfarin) on the growth of zebrafish embryos. They found that all five had the same effect, impairing the migration of bone-forming cells which resulted in the onset of facial malformation. Zebrafish embryos grow quickly, are transparent and develop outside of the parent's body, making them ideal for studying early development. A zebrafish-based system could be used to easily screen for potentially harmful substances, reducing animal testing on mammals and supporting parents-to-be when making choices for themselves and their baby.
Published Wearable device data reveals that reduced sleep and activity in pregnancy is linked to premature birth risk (via sciencedaily.com)
Data from wearables show that deviations from normal sleep and activity in pregnancy are connected to a risk for premature delivery, a new study found.
Published Compensation by healthy brain parts alleviates Parkinson symptoms (via sciencedaily.com)
In Parkinson's disease, the cerebral cortex can take over tasks from a deeper part of the brain that has been damaged, where cells that make dopamine have been lost. The strength of compensation by the cerebral cortex determines how many symptoms people have. Patients can stimulate this compensation through sports, for example, and thus slow down the disease process.
Published Drug trial shows reduced abnormal bone formation in those with fibrodysplasia ossificans progressiva (via sciencedaily.com)
A multisite, international phase 2 trial evaluating the investigational drug garetosmab has shown that it reduced soft-tissue flare-ups significantly and prevented new areas of abnormal bone formation in patients with fibrodysplasia ossificans progressiva (FOP).
Published New study provides evidence for more effective brain-based treatment of chronic back pain (via sciencedaily.com)
A new study may provide key answers to how to help people experiencing chronic back pain. The study examined the critical connection between the brain and pain for treating chronic pain. Specifically, they looked at the importance of pain attributions, which are people's beliefs about the underlying causes of their pain, to reduce chronic back pain severity.
Published Decoding the complexity of Alzheimer's disease (via sciencedaily.com)
Using more than 2 million cells from over 400 postmortem brain samples, researchers performed the largest-scale analysis of the genomic, epigenomic, and transcriptomic changes that occur in every cell type in the brains of Alzheimer's patients.
Published Grandparent childcare may not help the wellbeing of mums or reduce mother-child conflict, study suggests (via sciencedaily.com)
Grandparent childcare for toddlers doesn’t have an impact on the wellbeing of their mothers, a new study suggests.