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     (via sciencedaily.com)     Original source 

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a fatal motor neuron disease that causes people to gradually lose control of their muscles. There is no cure, and current treatments focus on reducing symptoms and providing supportive care. Researchers now show in an early clinical trial that the Parkinson's disease drug ropinirole is safe to use in ALS patients and delayed disease progression by 27.9 weeks on average.

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Portable ultrasound devices could provide an alternative to x-ray machines for diagnosing forearm fractures in children in a move that could alleviate waiting times for families in hospital emergency departments (ED). Researchers compared functional outcomes in children given an ultrasound and those who received an x-ray on a suspected distal forearm fracture. The team treated 270 children, aged between five and 15 years, during the randomized trial, which included a check-up 28 days later and another check-in at eight weeks. The findings show the majority of children had similar recoveries and returned to full physical function.

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Researchers have developed a low-cost, RNA-based technology to detect and measure biomarkers, which can help decode the body's physiology. The presence of protein biomarkers can indicate chronic or acute conditions, from arthritis to cancer to bacterial infections, for which conventional tests can cost anywhere from $100 to upwards of $1,000. The new technology can perform the same measurement for about a dollar.

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Some people live longer than others -- possibly due to a unique combination of bacteria in their intestines, new research concludes.

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Young babies make many squeals, vowel-like sounds, growls, and short word-like sounds such as 'ba' or 'aga.' Those precursors to speech or 'protophones' are later replaced with early words and, eventually, whole phrases and sentences. While some infants are naturally more 'talkative' than others, a new study confirms that there are differences between males and females in the number of those sounds.

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Researchers have partnered to create a first-of-its-kind open-source, reproducible analysis platform for pediatric brain tumors. With the help of thousands of genomically sequenced samples, researchers have used this platform to identify initial findings about genetic variants associated with poorer outcomes that could help guide future diagnostic and therapeutic advances.

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Links have been reported between schizophrenia and proteins produced by the immune system that can act against one's own body, known as autoantibodies. Researchers have now identified autoantibodies that target a 'synaptic adhesion protein' in a subset of patients with schizophrenia. When injected into mice, the autoantibodies caused many schizophrenia-related changes.

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About two-thirds of the risk for Alzheimer's disease (AD) is thought to arise from genetic influences, but about a third could be influenced by environment and lifestyle, opening the door for behavioral interventions that could delay or prevent pathophysiological changes that occur with AD. Now a new study in a mouse model of AD examines the effects of environmental enrichment on AD symptom progression and pathology.

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Researchers suggest a simple tweak to the first meal of the day might help people living with Type 2 diabetes (T2D) better control their blood sugar levels. Switching from a traditional western-style low-fat breakfast, like oatmeal, toast and fruit, to a low-carb meal higher in protein and fat, like eggs with bacon or cheese, can help people with T2D better manage their blood sugar for most of the day.

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Consuming nutritious food can improve metabolic health and delay aging. But what are the appropriate quantities of dietary macronutrients that can help achieve this? To answer this, researchers fed isocaloric diets with varying amounts of protein to young and middle-aged male mice. They found that the mice were metabolically healthier when fed moderate-protein diets. These findings could provide valuable insights into developing nutritional interventions and improving metabolic health in people.

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A group of world leading health and scientific experts are calling on the aviation industry to take action to protect passengers and aircrew from dangerous cabin fumes which they say have led to a new emerging disease. Led by former pilot and aviation health researcher, the specialists have released the first medical protocol of its kind to help treat those effected by contamination of the aircraft cabin breathing air supply and collect data on contamination events.

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The early stages of embryonic development contain many of life's mysteries. Unlocking these mysteries can help us better understand early development and birth defects, and help develop new regenerative medicine treatments. Researchers have now characterized a critical time in mammalian embryonic development using powerful and innovative imaging techniques.

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A scientific team has designed a strategy to fight obesity and diabetes in mice through ex vivo gene therapy which consists of implanting cells that have been manipulated and transformed in order to treat a disease. This is the first study to apply the ex vivo gene therapy technique to generate and implant cells that express the CPT1AM protein, an enzyme that plays a decisive role in many metabolic diseases such as obesity.

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Low sexual satisfaction in middle age may serve as an early warning sign for future cognitive decline, according to a new study. The study, which tracked associations between erectile function, sexual satisfaction and cognition in hundreds of men aged 56 through 68, found that declines in sexual satisfaction and erectile function were correlated with future memory loss.

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Being obese significantly increases the chances of also developing mental disorders. This applies to all age groups, with women at higher risk than men for most diseases.

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Complicated, hard-to-heal wounds are a growing medical problem and there are currently only two drugs approved with proven efficacy. In a new study on humans, researchers show that treatment with a specific type of modified lactic acid bacteria works well and has a positive effect on the healing of wounds.

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In a new study, researchers have investigated how junk food affects sleep. Healthy participants consumed an unhealthier as well as a healthier diet in a randomized order. After the unhealthier diet, the quality of the participants' deep sleep had deteriorated, compared with those who had followed the healthier diet.

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Age-related memory loss is likely caused, in part, by lack of flavanols -- nutrients found in certain fruits and vegetables -- according to a large study in older adults.

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Study from researchers at Western's Advanced Facility for Avian Research (AFAR), home to the world's first hypobaric climatic wind tunnel for bird flight, explores a brain region called cluster N that migratory birds use to perceive Earth's magnetic field. The team discovered the region is activated very flexibly, meaning these birds have an ability to process, or ignore, geomagnetic information, just as you may attend to music when you are interested or tune it out when you are not.

     (via sciencedaily.com)     Original source 

Using AI, researchers identified a new antibiotic that can kill Acinetobacter baumannii, a type of bacteria that is responsible for many drug-resistant infections.